HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species
HTRA1 分解 α-突触核蛋白淀粉样蛋白原纤维,并将其转化为无毒且无能力的物种
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-024-46538-8
Sheng Chen, Anuradhika Puri, Braxton Bell, Joseph Fritsche, Hector H Palacios, Maurie Balch, Macy L Sprunger, Matthew K Howard, Jeremy J Ryan, Jessica N Haines, Gary J Patti, Albert A Davis, Meredith E Jackrel