日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

BCMA-directed mRNA CAR-T cell therapy for myasthenia gravis: exploratory biomarker analysis of a placebo-controlled phase 2b trial.

BCMA 靶向 mRNA CAR-T 细胞疗法治疗重症肌无力:安慰剂对照 2b 期试验的探索性生物标志物分析。

Fedak Renee R, Ruggerie Rachel N, Shan Yufei, Curvino Elizabeth J, de Sousa Juliana F, Daniel Shaji, Ngo-Casi Minhtran, Kamboh Hafsa, Vu Tuan, Durmuş Hacer, Mozaffar Tahseen, Howard James F Jr, English Emily P, Benson Albina, Duvernay Matthew T, Singer Michael S, Kalayoglu Murat V, Brunn Carsten, Bodansky Aaron, Anderson Mark S, DeRisi Joseph L, Garcia Samantha T, Yu David J L, Zorn Kelsey C, Kurtoglu Metin, Miljković Miloš D, Stewart C Andrew, Jewell Christopher M

Atomically accurate de novo design of antibodies with RFdiffusion

利用射频扩散技术进行原子级精确的抗体从头设计

Bennett, Nathaniel R; Watson, Joseph L; Ragotte, Robert J; Borst, Andrew J; See, DéJenaé L; Weidle, Connor; Biswas, Riti; Yu, Yutong; Shrock, Ellen L; Ault, Russell; Leung, Philip J Y; Huang, Buwei; Goreshnik, Inna; Tam, John; Carr, Kenneth D; Singer, Benedikt; Criswell, Cameron; Wicky, Basile I M; Vafeados, Dionne; Garcia Sanchez, Mariana; Kim, Ho Min; Vázquez Torres, Susana; Chan, Sidney; Sun, Shirley M; Spear, Timothy T; Sun, Yi; O'Reilly, Keelan; Maris, John M; Sgourakis, Nikolaos G; Melnyk, Roman A; Liu, Chang C; Baker, David

An Autochthonous Model of Lung Cancer Identifies Requirements for Cellular Transformation in the Naked Mole Rat

裸鼹鼠肺癌自体模型揭示细胞转化的必要条件

Shepard, Alyssa; Lester, Daniel K; Troutman, Scott; Hoxha, Sany; Khaled, Walid T; Smith, Ewan St J; Park, Thomas J; Buffenstein, Rochelle; Du, Dongliang; Teng, Mingxiang; Dengler-Crish, Christine M; Tsai, Kenneth Y; Flores, Elsa R; Ventura, Andrea; Kissil, Joseph L

Altered MDC1 Interactions and Dysfunctional DNA Repair in Lobular Breast Cancer Confers Sensitivity to PARP Inhibition.

小叶乳腺癌中 MDC1 相互作用的改变和 DNA 修复功能障碍赋予了其对 PARP 抑制剂的敏感性。

Sottnik Joseph L, Shackleford Madeleine T, Nesiba Camryn S, Richer Amanda L, Fleischmann Zoe, Swartz Jordan M, Rowland Carmen E, Musick Maggie, Fu Rui, Myler Logan R, Opresko Patricia L, Mehrotra Sanjana, Sokol Ethan S, Hesselberth Jay R, Diamond Jennifer R, Sikora Matthew J

CXCR4-tropic HIV-1 infection in an immunocompetent monkey model

在免疫功能正常的猴模型中,CXCR4嗜性HIV-1感染

Meyerson, Nicholas R; Bauer, Vanessa L; Fattor, Will T; Warren, Cody J; Barbachano-Guerrero, Arturo; Weiss, Melisa J; Dirasantha, Obaiah; Burris, Bridget L; Adesina, Adetunji S; Timpona, Joseph L; Feldman, Emily R; Fahy, Ryan T; Gendler, Paul; Fainberg, Ava; Nehete, Pramod N; Shelton, Kathryn A; Galvan, Analy; Tustin, George W; Koehle, Paul J; Salinas, Maria D; Davila, Omar; Lindemann, Elizabeth I; Clark, Sean E; Garnett, Mackenzie L; DeMarco, C Todd; Scianna, Salvatore R; Denny, Thomas N; Kuhn, Jens H; Aye, Pyone P; Veazey, Ron S; Kezar, Sarah M; Wilkerson, Gregory K; Sawyer, Sara L

Accurate single-domain scaffolding of three nonoverlapping protein epitopes using deep learning

利用深度学习对三个不重叠的蛋白质表位进行精确的单域支架构建

Castro, Karla M; Watson, Joseph L; Wang, Jue; Southern, Joshua; Ayardulabi, Reyhaneh; Georgeon, Sandrine; Rosset, Stéphane; Baker, David; Correia, Bruno E

Validation of the Klinrisk Machine Learning Model for CKD Progression in a Large Representative US Population

在具有代表性的美国大型人群中验证Klinrisk机器学习模型对慢性肾病进展的预测能力

Tangri, Navdeep; Ferguson, Thomas W; Teng, Chia-Chen; Bamforth, Ryan J; Smith, Joseph L; Guzman, Maria; Goss, Ashley

The invisible divide: the impact of racial and geographic disparities on multiple myeloma outcomes - insights from a single-site study

无形的鸿沟:种族和地域差异对多发性骨髓瘤预后的影响——来自单中心研究的启示

Bauer, Michael A; Farmer, Phillip; Su, Joseph L; Schootman, Mario; Li, Chenghui; Van Rhee, Frits; Al Hadidi, Samer; Schinke, Carolina; Shaughnessy, John D; Zhan, Fenghuang; Ashby, Cody

Residential proximity to active and abandoned oil and gas development and risk of childhood Ewing sarcoma in California

加州居民居住在活跃或废弃的油气开发区附近与儿童尤文氏肉瘤风险相关

Clark, Cassandra J; Johnson, Nicholaus; Wang, Rong; Stewart, Eric C; Spector, Logan G; Wiemels, Joseph L; Metayer, Catherine; Deziel, Nicole C; Ma, Xiaomei

Relationship between genetically determined telomere length and childhood glioma risk

遗传决定的端粒长度与儿童神经胶质瘤风险之间的关系

Zhou, Naying; Li, Shaobo; Foss-Skiftesvik, Jon; Dahlin, Anna M; Bybjerg-Grauholm, Jonas; Melin, Beatrice; de Smith, Adam J; Walsh, Kyle M; Wiemels, Joseph L