日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hepatocyte-specific Epidermal Growth Factor Receptor Deletion Promotes Fibrosis but has no Effect on Steatosis in Fast-food Diet Model of Metabolic Dysfunction-associated Steatotic Liver Disease

肝细胞特异性表皮生长因子受体缺失促进纤维化,但对代谢功能障碍相关脂肪肝快餐饮食模型中的脂肪变性没有影响

Shehnaz Bano, Matthew A Copeland, John W Stoops, Anne Orr, Siddhi Jain, Shirish Paranjpe, Raja Gopal Reddy Mooli, Sadeesh K Ramakrishnan, Joseph Locker, Wendy M Mars, George K Michalopoulos, Bharat Bhushan

Antagonizing Activin A/p15INK4b Signaling as Therapeutic Strategy for Liver Disease

拮抗激活素 A/p15INK4b 信号作为肝病的治疗策略

Sowmya Mekala, Ravi Rai, Samantha Loretta Reed, Bill Bowen, George K Michalopoulos, Joseph Locker, Reben Raeman, Michael Oertel

Hepatocyte Smoothened Activity Controls Susceptibility to Insulin Resistance and Nonalcoholic Fatty Liver Disease

肝细胞平滑活性控制胰岛素抵抗和非酒精性脂肪肝的易感性

Tianyi Chen, George Dalton, Seh-Hoon Oh, Raquel Maeso-Diaz, Kuo Du, Rachel A Meyers, Cynthia Guy, Manal F Abdelmalek, Ricardo Henao, Paolo Guarnieri, Steven S Pullen, Simon Gregory, Joseph Locker, J Mark Brown, Anna Mae Diehl

Dysregulation of Lipid and Glucose Homeostasis in Hepatocyte-Specific SLC25A34 Knockout Mice

肝细胞特异性 SLC25A34 基因敲除小鼠的脂质和葡萄糖稳态失调

Nairita Roy, Frances Alencastro, Bayley A Roseman, Sierra R Wilson, Evan R Delgado, Meredith C May, Bharat Bhushan, Fiona M Bello, Michael J Jurczak, Sruti Shiva, Joseph Locker, Sebastien Gingras, Andrew W Duncan

Lymphocyte-Specific Protein-1 Suppresses Xenobiotic-Induced Constitutive Androstane Receptor and Subsequent Yes-Associated Protein-Activated Hepatocyte Proliferation

淋巴细胞特异性蛋白-1 抑制外来化合物诱导的组成性雄甾烷受体和随后的 Yes 相关蛋白激活的肝细胞增殖

Kelly Koral, Bharat Bhushan, Anne Orr, John Stoops, William C Bowen, Matthew A Copeland, Joseph Locker, Wendy M Mars, George K Michalopoulos

Targeted Inhibition of the E3 Ligase SCFSkp2/Cks1 Has Antitumor Activity in RB1-Deficient Human and Mouse Small-Cell Lung Cancer

靶向抑制 E3 连接酶 SCFSkp2/Cks1 对 RB1 缺陷的人类和小鼠小细胞肺癌具有抗肿瘤活性

Hongling Zhao, Niloy J Iqbal, Vineeth Sukrithan, Cari Nicholas, Yingjiao Xue, Cindy Yu, Joseph Locker, Juntao Zou, Edward L Schwartz, Liang Zhu

Constitutive Activation of the Human Aryl Hydrocarbon Receptor in Mice Promotes Hepatocarcinogenesis Independent of Its Coactivator Gadd45b

小鼠中人类芳基烃受体的组成性激活促进肝癌发生,而不依赖于其辅激活因子 Gadd45b

Peipei Lu, Xinran Cai, Yan Guo, Meishu Xu, Jianmin Tian, Joseph Locker, Wen Xie

Activin A is a prominent autocrine regulator of hepatocyte growth arrest

激活素 A 是肝细胞生长停滞的重要自分泌调节剂

Srividyameena Haridoss, Mladen I Yovchev, Hannah Schweizer, Sabreen Megherhi, Maria Beecher, Joseph Locker, Michael Oertel

Triple Staining Including FOXA2 Identifies Stem Cell Lineages Undergoing Hepatic and Biliary Differentiation in Cirrhotic Human Liver

包括 FOXA2 在内的三重染色可识别肝硬化人类肝脏中正在发生肝脏和胆道分化的干细胞谱系

Charles E Rogler, Remon Bebawee, Joe Matarlo, Joseph Locker, Nicole Pattamanuch, Sanjeev Gupta, Leslie E Rogler

Resetting the transcription factor network reverses terminal chronic hepatic failure

重置转录因子网络可逆转终末慢性肝功能衰竭

Taichiro Nishikawa, Aaron Bell, Jenna M Brooks, Kentaro Setoyama, Marta Melis, Bing Han, Ken Fukumitsu, Kan Handa, Jianmin Tian, Klaus H Kaestner, Yoram Vodovotz, Joseph Locker, Alejandro Soto-Gutierrez, Ira J Fox