日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intrawound Tobramycin Plus Vancomycin to Prevent Surgical Site Infection in Tibial Fractures: The TOBRA Randomized Clinical Trial

胫骨骨折手术部位感染的预防:伤口内注射妥布霉素联合万古霉素——TOBRA随机临床试验

O'Toole, Robert V; O'Hara, Nathan N; Carlini, Anthony R; Schrank, Gregory M; Chung, Suna; Gary, Joshua L; Obremskey, William; Matuszewski, Paul Edward; Teague, David; Natoli, Roman M; Gitajn, Ida Leah; Weaver, Michael J; Renninger, Christopher H; Levack, Ashley Elizabeth; Degani, Yasmin; Collins, Susan C; Weston-Farber, Elias; Howe, Andrea L; Thompson, Richard E; Castillo, Renan C; Karunakar, Madhav A; Blum, Laura; Harmer, Luke; Hsu, Joseph R; Kempton, Laurence B; Phelps, Kevin D; Seymour, Rachel B; Sims, Stephen H; Acharya, Maithili S; Callahan, Hayden; Chavez-Araujo, Luz M; Churchill, Christine; Gambuzza, Michael P; Haim, Kara R; Ishman, Enosh; Kendall, Joshua S; Mullis, Nicholas D; Young, Catherine; Pilson, Holly T; Carroll, Eben A; Goodman, James Brett; Holden, Martha B; Jones, Alan L; Moon, Charles; Lin, Carol A; Marecek, Geoffrey S; Moffitt, Gable B; Conlan, Todd; George, Albert V; Fisher, Lillian Adelaide; Mullin, Devin S; Recendez, Chelsey L; Aneja, Arun; Brameier, Devon T; Heng, Marilyn; Ly, Thuan V; Stenquist, Derek S; Suneja, Nishant; Wignakumar, Thirushan; Borgida, Jacob S; Policicchio, Thomas J; Hanson, George R; Alese, Olutayo M; Ricci, William M; Behrens, Steve B; Dvorzhinskiy, Aleksey; Bilodeau, Robert E; Klinger, Craig E; Mullis, Brian H; Jang, Yohan; Lopas, Luke A; McKinley, Todd O; O'Neill, Dillon C; Szatkowski, Jan P; Virkus, Walter W; Hill, Lauren C; Gaski, Greg; Hymes, Robert A; Ahn, James; Goch, Abraham M; Holzman, Michael; Malekzadeh, A Stephen; Schulman, Jeff E; Rivera, Jessica C; Krause, Peter C; Bridgman, Carolyn; Cohen, Joseph; Eikani, Carlo; Chavez, Maria; Kudulis, Michelle; Warner, Stephen J; Achor, Timothy S; Choo, Andrew; Eastman, Jonathan G; Kellam, Patrick J; Boutte, Sterling J; Guevara, Keyla Denniss; Reid, Kristoff R; Vallier, Heather A; Tucci, Anna Vergon; Davis, Jana M; Bell, Alice C; Bonyun, Marissa E; Healey, Kathleen; Li, Vivian; McKibben, Natasha S; Nascone, Jason; Okhuereigbe, David; Sciadini, Marcus F; Slobogean, Gerard; Zingas, Nicolas; Kovvur, Murali; Lawrence, Joshua E; Phipps, Heather; Rudnicki, Joshua; Turner, Kristin E; Hayda, Roman; Evans, Andrew R; Quinnan, Stephen; Benitez, Alyha; Rehman, Saqib; Soderquist, Melissa C; Townsend, Clay B; Caroom, Cyrus; Collins, Angela C; Okwumabua, Ebubechi; Shaikh, Humza S; Spitler, Clay A; Agarwal, Abhinav; Johnson, Michael D; Haller, Justin M; Marchand, Lucas S; Alfonso, Nicholas A; Gorman, Melissa A; Charlton, William Michael; Scott, Brandon R; Kraus, Kameron M; Meredith, Sean J; Talwar, Sneh; Bergin, Patrick F; Jha, Aaradhana J; McGee, Sheketha; Nehete, Priyanka V; Pryor, Tyranny A; Spears, Isaac; Chen, Andrew T; Kelley, Benjamin; Nez, Nevaeh R; Ertl, William J; Hull, Brandon R; Blumenthal, Sarah; Patterson, Joseph T; Flynn, Camille; Ross, Ryan C; Agarwal, Animesh; Weiss, David B; Hadeed, Michael M; Yarboro, Seth R; Daoud, Tina; McVey, Eric D; Whiting, Paul S; Domes, Christopher; Goodspeed, David C; Kuhn, Gabrielle R; Boyce, Robert; Libos, Andres; Mitchell, Phillip M; Moreno-Diaz, Andres Fidel; Ponce, Robert Brandon; Stinner, Daniel J; Tatman, Lauren M; Velasco-Castro, Juanita; Trochez, Karen; Satpathy, Jibanananda; Zuelzer, David A; Potter, Benjamin K

Antisense oligonucleotide-mediated knockdown therapy in two infants with severe KCNT1 epileptic encephalopathy

反义寡核苷酸介导的基因敲低疗法治疗两名患有严重KCNT1癫痫性脑病的婴儿

Nakayama, Tojo; El Achkar, Christelle M; Burbano, Lisseth E; Quraishi, Imran H; Wu, Jing; Li, Melody; Asami, Yutaro; Golinski, Sean R; Sherrill, Emma; Goodlett, Benjamin D; de Gusmao, Claudio M; Friedman, Danielle A; Lentucci, Claudia; Suslovitch, Victoria; Riccardi, Olivia; Faour, Kamli N W; Kuniholm, Ashley; Soucy Verran, Aubrie; Coffman, Siobhan; Ahtam, Banu; Zhao, Boxun; Chin, Diana H; DiDonato, Renata L; Hu, Chunguang A; Lopez, Edith; Hills, Sonia; Maljevic, Snezana; Tran, Helene; Bush, Lynn W; Grant, Patricia Ellen; Madsen, Joseph R; Smith, Richard S; Kaczmarek, Leonard K; Berde, Charles B; Yu, Timothy W

Cell-type-specific transposon demethylation and TAD remodeling in aging mouse brain

衰老小鼠脑中细胞类型特异性转座子去甲基化和TAD重塑

Zeng, Qiurui; Wang, Wenliang; Tian, Wei; Klein, Amit; Bartlett, Anna; Liu, Hanqing; Nery, Joseph R; Castanon, Rosa G; Osteen, Julia; Johnson, Nicholas D; Ding, Wubin; Chen, Huaming; Altshul, Jordan; Kenworthy, Mia; Valadon, Cynthia; Owens, William; Wu, Zhanghao; Amaral, Maria Luisa; Zemke, Nathan R; Song, Yuru; Báez-Becerra, Cindy Tatiana; Cho, Silvia; Chen, Chumo; Willier, Jackson; Cao, Stella; Rink, Jonathan; Lee, Jasper; Barcoma, Ariana; Arzavala, Jessica; Emerson, Nora; Lu, Yuancheng Ryan; Ren, Bing; Behrens, M Margarita; Ecker, Joseph R

Genetics and environment distinctively shape the human immune cell epigenome

遗传和环境共同塑造了人类免疫细胞的表观基因组。

Wang, Wenliang; Hariharan, Manoj; Ding, Wubin; Bartlett, Anna; Barragan, Cesar; Castanon, Rosa; Wang, Ruoxuan; Rothenberg, Vince; Song, Haili; Nery, Joseph R; Aldridge, Andrew; Altshul, Jordan; Kenworthy, Mia; Liu, Hanqing; Tian, Wei; Zhou, Jingtian; Zeng, Qiurui; Chen, Huaming; Wei, Bei; Gündüz, Irem B; Norell, Todd; Broderick, Timothy J; McClain, Micah T; Satterwhite, Lisa L; Burke, Thomas W; Petzold, Elizabeth A; Shen, Xiling; Woods, Christopher W; Fowler, Vance G Jr; Ruffin, Felicia; Panuwet, Parinya; Barr, Dana B; Beare, Jennifer L; Smith, Anthony K; Spurbeck, Rachel R; Vangeti, Sindhu; Ramos, Irene; Nudelman, German; Sealfon, Stuart C; Castellino, Flora; Walley, Anna Maria; Evans, Thomas; Müller, Fabian; Greenleaf, William J; Ecker, Joseph R

Semi-Reduction of Allenes to Access Deuterated Allylic Isotopomers, Isotopologs and Enantioisotopomers

丙二烯半还原法制备氘代烯丙基同位素异构体、同位素类似物和对映体

Qi, Lihan; Thorat, Raviraj Ananda; Maxwell, Brad D; Gladding, Jeffery A; Arzola, Aniel J Rivera; Sancheti, Shashank P; Sonstrom, Reilly E; Tang, Xulin; Anderson, Isaac J; Pate, Brooks H; Clark, Joseph R

STING/type I interferon pathway is required for antigen-containing PLGA nanoparticle- and apoptotic cell-induced CD4+ T cell tolerance

STING/I型干扰素通路是含抗原PLGA纳米颗粒和凋亡细胞诱导CD4+T细胞耐受所必需的。

Podojil, Joseph R; Cogswell, Andrew C; Neef, Tobias; Chiang, Ming-Yi; Beddow, Sara A; Arellano, Gabriel; Kakade, Sandeep; McCarthy, Derrick P; Elhofy, Adam; Harp, Chris T; Khan, Mairah; Meeks, Joshua J; Xu, Dan; Shea, Lonnie D; Miller, Stephen D

Characterizing amyloid and tau positron emission tomography-based stages across the clinical continuum

在临床连续过程中,对基于正电子发射断层扫描的淀粉样蛋白和tau蛋白阶段进行表征

Cody, Karly A; Sokołowski, Andrzej; Johns, Emily; Guerra, Lucah Medina; Winer, Joseph R; Young, Christina B; Younes, Kyan; Dumitrescu, Logan; Archer, Derek B; Durant, Alaina; Sathe, Aditi; Koran, Mary Ellen I; Mez, Jesse; Saykin, Andrew J; Toga, Arthur; Cuccaro, Michael; Tosun, Duygu; Insel, Philip S; Johnson, Sterling C; Harrison, Theresa M; Hohman, Timothy J; Mormino, Elizabeth C

Wake-promoting neuromodulators in Alzheimer's disease: Implications for sleep and brain clearance

阿尔茨海默病中促进觉醒的神经调节剂:对睡眠和大脑清除的影响

Pedersen, Taylor J; Clemens, Sabrina G; Winer, Joseph R; Sharma, Ashish; Falgàs, Neus; Lucey, Brendan P; Gordon, Brian A; Musiek, Erik S

Cognitive screening biases in a secondary prevention Alzheimer's disease clinical trial

阿尔茨海默病二级预防临床试验中的认知筛查偏差

Sai, Isha; Grill, Joshua D; Younes, Kyan; Winer, Joseph R; Cody, Karly A; Sperling, Reisa; Mormino, Elizabeth C; Young, Christina B

Discovery of BMS-986365, a First-in-Class Dual Androgen Receptor Ligand-Directed Degrader and Antagonist, for the Treatment of Advanced Prostate Cancer.

发现 BMS-986365,一种首创的双重雄激素受体配体导向降解剂和拮抗剂,用于治疗晚期前列腺癌。

Nayak Surendra, Norris John D, Ammirante Massimo, Rychak Emily, Wardell Suzanne E, Liao Debbie, Toyama Brandon, Kandimalla Raju, Christoforou Andy, Tsuji Toshiya, Liu Ken, Tran Minerva, Meiring Joseph, Reiss Samantha, Piccotti Joseph R, Baughman Joshua M, Fontanillo Celia, Khater Marwa, Mortensen Deborah S, Cathers Brian, Bence Neil, Pierce Daniel W, Plantevin-Krenitsky Veronique, Rathkopf Dana, Hansen Joshua D, Hamann Lawrence G, Narla Rama Krishna, Arora Vivek K, McDonnell Donald P, Rolfe Mark, Xu Shuichan