日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PALB2 and 53BP1 govern post-resection homologous recombination DNA repair

PALB2 和 53BP1 调控切除后同源重组 DNA 修复

Yifan Wang ,Yan Coulombe ,Wei-Ting Yueh ,Gregory D Conway ,Larissa Milano ,David J Glass ,Mélissa Thomas ,Amélie Rodrigue ,Joseph Nacson ,Dongbo Lu ,Andrea J Bernhardy ,Robert G Betsch ,Alyssa I Russo ,Gamal A Elfar ,Kathy Q Cai ,Joseph R Testa ,Mark Andrake ,Roland Dunbrack ,Gaorav P Gupta ,Bing Xia ,Eloise Dray ,Jean-Yves Masson ,Neil Johnson

Spatial Landscape of Malignant Pleural and Peritoneal Mesothelioma Tumor Immune Microenvironments

恶性胸膜和腹膜间皮瘤肿瘤免疫微环境的空间景观

Xiaojun Ma, David Lembersky, Elena S Kim, Michael J Becich, Joseph R Testa, Tullia C Bruno, Hatice U Osmanbeyoglu

Low Exposures to Amphibole or Serpentine Asbestos in Germline Bap1-mutant Mice Induce Mesothelioma Characterized by an Immunosuppressive Tumor Microenvironment

种系 Bap1 突变小鼠低剂量接触闪石或蛇纹石石棉可诱发以免疫抑制肿瘤微环境为特征的间皮瘤

Yuwaraj Kadariya, Eleonora Sementino, Maggie Ruan, Mitchell Cheung, Parham Hadikhani, Hatice U Osmanbeyoglu, Andres J Klein-Szanto, Kathy Cai, Joseph R Testa

Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities

Brca1 功能的遗传分离揭示了突变依赖的 Polθ 脆弱性

John J Krais, David J Glass, Ilse Chudoba, Yifan Wang, Wanjuan Feng, Dennis Simpson, Pooja Patel, Zemin Liu, Ryan Neumann-Domer, Robert G Betsch, Andrea J Bernhardy, Alice M Bradbury, Jason Conger, Wei-Ting Yueh, Joseph Nacson, Richard T Pomerantz, Gaorav P Gupta, Joseph R Testa, Neil Johnson

BAP1 maintains HIF-dependent interferon beta induction to suppress tumor growth in clear cell renal cell carcinoma

BAP1维持HIF依赖的干扰素β诱导,从而抑制透明细胞肾细胞癌的肿瘤生长。

Lauren E Langbein ,Rayan El Hajjar ,Shen He ,Eleonora Sementino ,Zhijiu Zhong ,Wei Jiang ,Benjamin E Leiby ,Li Li ,Robert G Uzzo ,Joseph R Testa ,Haifeng Yang

Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling

p21 活化激酶 2 (Pak2) 的失活通过限制下游 Hedgehog 和 Wnt 信号传导来抑制 Nf2 缺陷肿瘤的发展

Eleonora Sementino #, Yuwaraj Kadariya #, Mitchell Cheung, Craig W Menges, Yinfei Tan, Anna-Mariya Kukuyan, Ujjawal Shrestha, Sofiia Karchugina, Kathy Q Cai, Suraj Peri, James S Duncan, Jonathan Chernoff, Joseph R Testa

Inflammation as a chemoprevention target in asbestos-induced malignant mesothelioma

炎症作为石棉诱发的恶性间皮瘤化学预防目标

Yuwaraj Kadariya, Eleonora Sementino, Ujjawal Shrestha, Greg Gorman, Jonathan M White, Eric A Ross, Margie L Clapper, Nouri Neamati, Mark Steven Miller, Joseph R Testa

Data supporting the roles of BAP1, STING, and IFN-β in ISGF3 activation in ccRCC

支持 BAP1、STING 和 IFN-β 在 ccRCC 中 ISGF3 激活中的作用的数据

Lauren E Langbein, Eleonora Sementino, Zhijiu Zhong, Wei Jiang, Li Li, Joseph R Testa, Haifeng Yang

Synthetic Secoisolariciresinol Diglucoside (LGM2605) Prevents Asbestos-Induced Inflammation and Genotoxic Cell Damage in Human Mesothelial Cells

合成 Secoisolariciresinol 二葡萄糖苷 (LGM2605) 可预防人类间皮细胞中石棉引起的炎症和基因毒性细胞损伤

Ralph A Pietrofesa, Shampa Chatterjee, Yuwaraj Kadariya, Joseph R Testa, Steven M Albelda, Melpo Christofidou-Solomidou

Mesothelioma Mouse Models with Mixed Genomic States of Chromosome and Microsatellite Instability

具有染色体和微卫星不稳定性的混合基因组状态的间皮瘤小鼠模型

Yurong Song, Shaneen S Baxter, Lisheng Dai, Chelsea Sanders, Sandra Burkett, Ryan N Baugher, Stephanie D Mellott, Todd B Young, Heidi E Lawhorn, Simone Difilippantonio, Baktiar Karim, Yuwaraj Kadariya, Ligia A Pinto, Joseph R Testa, Robert H Shoemaker