日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Affecting HEK293 Cell Growth and Production Performance by Modifying the Expression of Specific Genes

通过修改特定基因的表达来影响HEK293细胞的生长和生产性能

Laura Abaandou, David Quan, Joseph Shiloach

Knockout of the caspase 8-associated protein 2 gene improves recombinant protein expression in HEK293 cells through up-regulation of the cyclin-dependent kinase inhibitor 2A gene

敲除胱天蛋白酶 8 相关蛋白 2 基因可通过上调细胞周期蛋白依赖性激酶抑制剂 2A 基因来改善 HEK293 细胞中的重组蛋白表达

Laura Abaandou, Ashish K Sharma, Joseph Shiloach

Effect of restricted dissolved oxygen on expression of Clostridium difficile toxin A subunit from E. coli

溶解氧受限对大肠杆菌艰难梭菌毒素A亚基表达的影响

Ashish K Sharma, Jenie Phue, Emir Khatipov, Nimish Dalal, Eric D Anderson, Joseph Shiloach

Improved protein expression in HEK293 cells by over-expressing miR-22 and knocking-out its target gene, HIPK1

通过过度表达 miR-22 并敲除其靶基因 HIPK1 来改善 HEK293 细胞中的蛋白质表达

Sarah Inwood, Laura Abaandou, Michael Betenbaugh, Joseph Shiloach

Expression of multidrug transporter P-glycoprotein in Pichia pastoris affects the host's methanol metabolism

毕赤酵母中多药转运体P-糖蛋白的表达对宿主甲醇代谢的影响

Wan-Cang Liu, Fei Zhou, Di Xia, Joseph Shiloach

A genetic model to study O- GlcNAc cycling in immortalized mouse embryonic fibroblasts

研究永生化小鼠胚胎成纤维细胞中 O-GlcNAc 循环的遗传模型

Melissa M St Amand, Michelle R Bond, Julia Riedy, Marcella Comly, Joseph Shiloach, John A Hanover

Effect of over expressing protective antigen on global gene transcription in Bacillus anthracis BH500

过量表达保护性抗原对炭疽芽孢杆菌BH500基因转录的影响

Ashish K Sharma, Stephen H Leppla, Andrei P Pomerantsev, Joseph Shiloach

Identifying HIPK1 as Target of miR-22-3p Enhancing Recombinant Protein Production From HEK 293 Cell by Using Microarray and HTP siRNA Screen

利用微阵列和 HTP siRNA 筛选确定 HIPK1 为 miR-22-3p 的靶点,从而增强 HEK 293 细胞的重组蛋白产量

Sarah Inwood, Eugen Buehler, Michael Betenbaugh, Madhu Lal, Joseph Shiloach

Genome-Wide High-Throughput RNAi Screening for Identification of Genes Involved in Protein Production

全基因组高通量 RNAi 筛选,用于鉴定参与蛋白质生产的基因

Sarah Inwood, Michael J Betenbaugh, Madhu Lal, Joseph Shiloach

Knocking out Ornithine Decarboxylase Antizyme 1 (OAZ1) Improves Recombinant Protein Expression in the HEK293 Cell Line

敲除鸟氨酸脱羧酶抗酶 1 (OAZ1) 可改善 HEK293 细胞系中的重组蛋白表达

Laura Abaandou, Joseph Shiloach