日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound.

恶性疟原虫快速进化的 FIKK 激酶家族可被单一化合物抑制

Belda Hugo, Bradley David, Christodoulou Evangelos, Nofal Stephanie D, Broncel Malgorzata, Jones David, Davies Heledd, Bertran M Teresa, Purkiss Andrew G, Ogrodowicz Roksana W, Joshi Dhira, O'Reilly Nicola, Walport Louise, Powell Andrew, House David, Kjaer Svend, Claessens Antoine, Landry Christian R, Treeck Moritz

PDZ-directed substrate recruitment is the primary determinant of specific 4E-BP1 dephosphorylation by PP1-Neurabin.

PDZ 导向的底物募集是 PP1-Neurabin 特异性地使 4E-BP1 去磷酸化的主要决定因素

Fedoryshchak Roman O, El-Bouri Karim, Joshi Dhira, Mouilleron Stephane, Treisman Richard

Author Correction: Characterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110α

作者更正:对一种与磷脂酰肌醇3-激酶p110α的RAS结合域结合的环状肽进行表征

Ismail, Mohamed; Martin, Stephen R; George, Roger; Houghton, Francesca; Kelly, Geoff; Chaleil, Raphaël A G; Anastasiou, Panayiotis; Wang, Xinyue; O'Reilly, Nicola; Federico, Stefania; Joshi, Dhira; Nagaraj, Hemavathi; Cooley, Rachel; Hui, Ning Sze; Molina-Arcas, Miriam; Hancock, David C; Tavassoli, Ali; Downward, Julian

O-Linked Sialoglycans Modulate the Proteolysis of SARS-CoV-2 Spike and Likely Contribute to the Mutational Trajectory in Variants of Concern

O-连接的唾液酸聚糖调节SARS-CoV-2刺突蛋白的蛋白水解,并可能导致相关变异株的突变轨迹。

Gonzalez-Rodriguez, Edgar; Zol-Hanlon, Mia; Bineva-Todd, Ganka; Marchesi, Andrea; Skehel, Mark; Mahoney, Keira E; Roustan, Chloë; Borg, Annabel; Di Vagno, Lucia; Kjær, Svend; Wrobel, Antoni G; Benton, Donald J; Nawrath, Philipp; Flitsch, Sabine L; Joshi, Dhira; González-Ramírez, Andrés Manuel; Wilkinson, Katalin A; Wilkinson, Robert J; Wall, Emma C; Hurtado-Guerrero, Ramón; Malaker, Stacy A; Schumann, Benjamin

Corrigendum to Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity

关于 SCOC 的 LIR 结构域磷酸化调节 ATG8 结合亲和力和特异性的更正

Wirth, Martina; Mouilleron, Stephane; Zhang, Wenxin; Sjøttem, Eva; Abudu, Yakubu Princely; Jain, Ashish; Olsvik, Hallvard Lauritz; Bruun, Jack-Ansgar; Razi, Minoo; Jefferies, Harold B J; Lee, Rebecca; Joshi, Dhira; O'Reilly, Nicola; Johansen, Terje; Tooze, Sharon A

Fluorescent Amino Acid Initiated de novo Cyclic Peptides for the Label-Free Assessment of Cell Permeability*

荧光氨基酸引发的从头合成环肽用于无标记评估细胞通透性*

Wu, Yuteng; Bertran, M Teresa; Rowley, James; Calder, Ewen D D; Joshi, Dhira; Walport, Louise J

Glypicans shield the Wnt lipid moiety to enable signalling at a distance

糖蛋白聚糖能够保护Wnt脂质部分,从而实现远距离信号传导。

McGough, Ian J; Vecchia, Luca; Bishop, Benjamin; Malinauskas, Tomas; Beckett, Karen; Joshi, Dhira; O'Reilly, Nicola; Siebold, Christian; Jones, E Yvonne; Vincent, Jean-Paul

Preexisting and de novo humoral immunity to SARS-CoV-2 in humans

人类体内针对SARS-CoV-2的既有和新生体液免疫

Ng, Kevin W; Faulkner, Nikhil; Cornish, Georgina H; Rosa, Annachiara; Harvey, Ruth; Hussain, Saira; Ulferts, Rachel; Earl, Christopher; Wrobel, Antoni G; Benton, Donald J; Roustan, Chloe; Bolland, William; Thompson, Rachael; Agua-Doce, Ana; Hobson, Philip; Heaney, Judith; Rickman, Hannah; Paraskevopoulou, Stavroula; Houlihan, Catherine F; Thomson, Kirsty; Sanchez, Emilie; Shin, Gee Yen; Spyer, Moira J; Joshi, Dhira; O'Reilly, Nicola; Walker, Philip A; Kjaer, Svend; Riddell, Andrew; Moore, Catherine; Jebson, Bethany R; Wilkinson, Meredyth; Marshall, Lucy R; Rosser, Elizabeth C; Radziszewska, Anna; Peckham, Hannah; Ciurtin, Coziana; Wedderburn, Lucy R; Beale, Rupert; Swanton, Charles; Gandhi, Sonia; Stockinger, Brigitta; McCauley, John; Gamblin, Steve J; McCoy, Laura E; Cherepanov, Peter; Nastouli, Eleni; Kassiotis, George