文献库，生知库 | 链接生命科学的每一步

日期影响因子

ERG-deficient endothelium identifies IL-8/CXCR2 axis as a therapeutic target for resolving neutrophilic lung vascular injury

ERG缺陷型内皮细胞表明IL-8/CXCR2轴是治疗中性粒细胞性肺血管损伤的潜在靶点

期刊:JCI Insight

影响因子:6.1

doi:10.1172/jci.insight.195989

Vellingiri, Vigneshwaran; Ragunathrao, Vijay Avin Balaji; Joshi, Jagdish Chandra; Akhter, Md Zahid; Anwar, Mumtaz; Banerjee, Somenath; Datta, Sayanti; Pinneker, Viktor; Dudek, Steven; Tsukasaki, Yoshikazu; Pinho, Sandra; Mehta, Dolly

中性粒细胞

细胞生物学

发表日期：2026

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Repolarization of inflammatory macrophages into reparative stage targeting cannabinoid receptor2: a potential perspective to dampen lung injury/ARDS

通过靶向大麻素受体2诱导炎症巨噬细胞重极化为修复阶段：一种减轻肺损伤/急性呼吸窘迫综合征的潜在方法

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2025.1623857

Benedict, Chloe; Joshi, Jagdish Chandra

细胞生物学

免疫/内分泌

发表日期：2025

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A Single Mutation in TRPC6 Protects Mice from Acute Lung Injury by Regenerating Endothelium

TRPC6基因的单个突变可通过再生内皮细胞保护小鼠免受急性肺损伤。

doi:10.1101/2025.02.19.639142

Anwar, Mumtaz; Balaji Raghunathrao, Vijay Avin; Amin, Ruhul; Vellingiri, Vigneshwaran; Joshi, Jagdish Chandra; Akhter, Md Zahid; Tauseef, Mohammad; El-Erian, Ibrahim Hassan; Khaki, Nazanin; Fancher, Ibra S; Abdelkarim, Hazem; Levitan, Irena; Chronis, Konstantinos; Gaponenko, Vadim; Mehta, Dolly

细胞生物学

发表日期：2025

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Endothelial ERG programs neutrophil transcriptome for sustained anti-inflammatory vascular niche

内皮细胞ERG调控中性粒细胞转录组，以维持抗炎血管微环境。

doi:10.1101/2024.05.02.591799

Vellingiri, Vigneshwaran; Balaji Ragunathrao, Vijay Avin; Joshi, Jagdish Chandra; Akhter, Md Zahid; Anwar, Mumtaz; Banerjee, Somenath; Dudek, Steven; Tsukasaki, Yoshikazu; Pinho, Sandra; Mehta, Dolly

细胞生物学

中性粒细胞

发表日期：2024

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RGS2 is an innate immune checkpoint for TLR4 and Gαq-mediated IFNγ generation and lung injury

RGS2是TLR4和Gαq介导的IFNγ生成和肺损伤的固有免疫检查点。

doi:10.1101/2023.09.22.559016

Joshi, Jagdish Chandra; Joshi, Bhagwati; Zhang, Cuiping; Banerjee, Somenath; Vellingiri, Vigneshwaran; Raghunathrao, Vijay Avin Balaji; Zhang, Lianghui; Amin, Ruhul; Song, Yuanlin; Mehta, Dolly

免疫/内分泌

发表日期：2023

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Regulation of cGAS Activity and Downstream Signaling

cGAS活性及其下游信号的调控

影响因子:5.2

doi:10.3390/cells11182812

Joshi, Bhagwati; Joshi, Jagdish Chandra; Mehta, Dolly

发表日期：2022

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Protease-activated receptor 2 promotes clearance of Pseudomonas aeruginosa infection by inducing cAMP-Rac1 signaling in alveolar macrophages

蛋白酶激活受体2通过诱导肺泡巨噬细胞中的cAMP-Rac1信号通路促进铜绿假单胞菌感染的清除

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2022.874197

Rayees, Sheikh; Joshi, Jagdish Chandra; Joshi, Bhagwati; Vellingiri, Vigneshwaran; Banerjee, Somenath; Mehta, Dolly

GPCR/Calcium/cAMP

细胞生物学

免疫/内分泌

发表日期：2022

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Macrophage TLR4 and PAR2 Signaling: Role in Regulating Vascular Inflammatory Injury and Repair

巨噬细胞TLR4和PAR2信号通路：在调节血管炎症损伤和修复中的作用

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2020.02091

Rayees, Sheikh; Rochford, Ian; Joshi, Jagdish Chandra; Joshi, Bhagwati; Banerjee, Somenath; Mehta, Dolly

细胞生物学

免疫/内分泌

发表日期：2020

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Noncanonical function of long myosin light chain kinase in increasing ER-PM junctions and augmentation of SOCE

长肌球蛋白轻链激酶的非经典功能在增加内质网-质膜连接和增强SOCE中的作用。

期刊:FASEB Journal

影响因子:4.4

doi:10.1096/fj.201902462RR

Nityanand Srivastava ，Mohammad Tauseef ，Ruhul Amin ，Bhagwati Joshi ，Jagdish Chandra Joshi ，Vidisha Kini ，Jennifer Klomp ，Weenan Li ，Nebojsa Knezevic ，Nicolas Barbera ，Shahid Siddiqui ，Alexander Obukhov ，Andrei Karginov ，Irena Levitan ，Yulia Komarova ，Dolly Mehta

发表日期：2020

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PAR2-Mediated cAMP Generation Suppresses TRPV4-Dependent Ca(2+) Signaling in Alveolar Macrophages to Resolve TLR4-Induced Inflammation.

PAR2 介导的 cAMP 生成抑制肺泡巨噬细胞中 TRPV4 依赖的 Ca(2+) 信号传导，从而消除 TLR4 诱导的炎症

期刊:Cell Reports

影响因子:6.9

doi:10.1016/j.celrep.2019.03.053

Rayees Sheikh, Joshi Jagdish Chandra, Tauseef Mohammad, Anwar Mumtaz, Baweja Sukriti, Rochford Ian, Joshi Bhagwati, Hollenberg Morley D, Reddy Sekhar P, Mehta Dolly

细胞生物学

发表日期：2019

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