日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A general one-step protocol to generate impermeable fluorescent HaloTag substrates for in situ live cell application and super-resolution imaging

一种用于原位活细胞应用和超分辨率成像的通用一步法制备不透膜荧光HaloTag底物的方法

Kilian Roßmann,Ulrich Pabst,Bianca C Baciu,Siqi Sun,Christiane Huhn,Christina Holmboe Olesen,Maria Kowald,Eleni Tapp,Marie Bieck,Ramona Birke,Brenda C Shields,Pyeonghwa Jeong,Jiyong Hong,Michael R Tadross,Joshua Levitz,Martin Lehmann,Noa Lipstein,Johannes Broichhagen

An epigenetic barrier sets the timing of human neuronal maturation

表观遗传屏障决定了人类神经元成熟的时间。

Gabriele Ciceri ,Arianna Baggiolini ,Hyein S Cho ,Meghana Kshirsagar ,Silvia Benito-Kwiecinski ,Ryan M Walsh ,Kelly A Aromolaran ,Alberto J Gonzalez-Hernandez ,Hermany Munguba ,So Yeon Koo ,Nan Xu ,Kaylin J Sevilla ,Peter A Goldstein ,Joshua Levitz ,Christina S Leslie # ,Richard P Koche # ,Lorenz Studer

Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons

联合小分子治疗加速人类多能干细胞衍生的神经元的成熟

Emiliano Hergenreder #, Andrew P Minotti #, Yana Zorina, Polina Oberst, Zeping Zhao, Hermany Munguba, Elizabeth L Calder, Arianna Baggiolini, Ryan M Walsh, Conor Liston, Joshua Levitz, Ralph Garippa, Shuibing Chen, Gabriele Ciceri, Lorenz Studer

Structural basis of positive allosteric modulation of metabotropic glutamate receptor activation and internalization

代谢型谷氨酸受体活化和内化的正变构调节的结构基础

Alexa Strauss #, Alberto J Gonzalez-Hernandez #, Joon Lee, Nohely Abreu, Purushotham Selvakumar, Leslie Salas-Estrada, Melanie Kristt, Anisul Arefin, Kevin Huynh, Dagan C Marx, Kristen Gilliland, Bruce J Melancon, Marta Filizola, Joel Meyerson, Joshua Levitz

Profiling the proximal proteome of the activated μ-opioid receptor

分析激活的 μ-阿片受体的近端蛋白质组

Benjamin J Polacco #, Braden T Lobingier #, Emily E Blythe, Nohely Abreu, Prachi Khare, Matthew K Howard, Alberto J Gonzalez-Hernandez, Jiewei Xu, Qiongyu Li, Brandon Novy, Zun Zar Chi Naing, Brian K Shoichet, Willow Coyote-Maestas, Joshua Levitz, Nevan J Krogan, Mark Von Zastrow, Ruth Hüttenhain

Synaptic plasticity via receptor tyrosine kinase/G-protein-coupled receptor crosstalk

通过受体酪氨酸激酶/G 蛋白偶联受体串扰实现突触可塑性

Cristina Lao-Peregrin, Guoqing Xiang, Jihye Kim, Ipsit Srivastava, Alexandra B Fall, Danielle M Gerhard, Piia Kohtala, Daegeon Kim, Minseok Song, Mikel Garcia-Marcos, Joshua Levitz, Francis S Lee

Dissecting the molecular basis for the modulation of neurotransmitter GPCR signaling by GINIP

解析GINIP调控神经递质GPCR信号传导的分子机制

Alex Luebbers ,Alberto J Gonzalez-Hernandez ,Myles Zhou ,Stephen J Eyles ,Joshua Levitz ,Mikel Garcia-Marcos

The MRAP2 accessory protein directly interacts with melanocortin-3 receptor to enhance signaling

MRAP2 辅助蛋白直接与黑皮质素-3 受体相互作用,增强信号传导

Aqfan Jamaluddin, Rachael A Wyatt, Joon Lee, Georgina K C Dowsett, John A Tadross, Johannes Broichhagen, Giles S H Yeo, Joshua Levitz, Caroline M Gorvin

Elevating levels of the endocannabinoid 2-arachidonoylglycerol blunts opioid reward but not analgesia

内源性大麻素 2-花生四烯酸甘油酯水平升高会减弱阿片类药物的奖励作用,但不会抑制镇痛作用

Arlene Martínez-Rivera, Robert N Fetcho, Lizzie Birmingham, Jin X Jiu, Ruirong Yang, Careen Foord, Diego Scala-Chávez, Narmin Mekawy, Kristen Pleil, Virginia M Pickel, Conor Liston, Carlos M Castorena, Joshua Levitz, Ying-Xian Pan, Lisa A Briand, Anjali M Rajadhyaksha, Francis S Lee

Projection-Targeted Photopharmacology Reveals Distinct Anxiolytic Roles for Presynaptic mGluR2 in Prefrontal- and Insula-Amygdala Synapses

投射靶向光药理学揭示了前额叶和岛叶杏仁核突触中突触前 mGluR2 的不同抗焦虑作用

Hermany Munguba, Vanessa A Gutzeit, Ipsit Srivastava, Melanie Kristt, Ashna Singh, Akshara Vijay, Anisul Arefin, Sonal Thukral, Johannes Broichhagen, Joseph M Stujenske, Conor Liston, Joshua Levitz