日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Distinct Replication Kinetics, Cytopathogenicity, and Immune Gene Regulation in Human Microglia Cells Infected with Asian and African Lineages of Zika Virus

感染亚洲和非洲谱系寨卡病毒的人类小胶质细胞中存在不同的复制动力学、细胞致病性和免疫基因调控

Ian M Bird, Victoria Cavener, Meera Surendran Nair, Ruth H Nissly, Shubhada K Chothe, Joshy Jacob, Suresh V Kuchipudi

A wild boar cathelicidin peptide derivative inhibits severe acute respiratory syndrome coronavirus-2 and its drifted variants

野猪抗菌肽衍生物可抑制严重急性呼吸综合征冠状病毒2及其变异株

Troy von Beck, Karla Navarrete, Nicholas A Arce, Mu Gao, Gordon A Dale, Meredith E Davis-Gardner, Katharine Floyd, Luis Mena Hernandez, Nikita Mullick, Abigail Vanderheiden, Ioanna Skountzou, Suresh V Kuchipudi, Rathi Saravanan, Renhao Li, Jeffrey Skolnick, Mehul S Suthar, Joshy Jacob

Atovaquone and Pibrentasvir Inhibit the SARS-CoV-2 Endoribonuclease and Restrict Infection In Vitro but Not In Vivo

阿托伐醌和哌仑他韦在体外抑制SARS-CoV-2核糖核酸内切酶并限制感染,但在体内则无此作用。

Troy von Beck ,Luis Mena Hernandez ,Hongyi Zhou ,Katharine Floyd ,Mehul S Suthar ,Jeffrey Skolnick ,Joshy Jacob

The amphibian peptide Yodha is virucidal for Zika and dengue viruses

两栖动物肽 Yodha 具有杀灭寨卡病毒和登革热病毒的功效

Song Hee Lee, Eui Ho Kim, Justin T O'neal, Gordon Dale, David J Holthausen, James R Bowen, Kendra M Quicke, Ioanna Skountzou, Shyla Gopal, Sanil George, Jens Wrammert, Mehul S Suthar, Joshy Jacob

Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway

基于角鲨烯乳剂的疫苗佐剂通过RIPK3依赖性途径刺激CD8 T细胞反应,但不刺激抗体反应。

Eui Ho Kim # ,Matthew C Woodruff # ,Lilit Grigoryan ,Barbara Maier ,Song Hee Lee ,Pratyusha Mandal ,Mario Cortese ,Muktha S Natrajan ,Rajesh Ravindran ,Huailiang Ma ,Miriam Merad ,Alexander D Gitlin ,Edward S Mocarski ,Joshy Jacob ,Bali Pulendran

Clustered Mutations at the Murine and Human IgH Locus Exhibit Significant Linkage Consistent with Templated Mutagenesis

小鼠和人类IgH基因座的簇状突变表现出显著的连锁性,这与模板诱变一致。

Gordon A Dale ,Daniel J Wilkins ,Caitlin D Bohannon ,Dario Dilernia ,Eric Hunter ,Trevor Bedford ,Rustom Antia ,Ignacio Sanz ,Joshy Jacob

Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection

长寿抗原诱导的 IgM 浆细胞表现出体细胞突变并有助于长期保护

Caitlin Bohannon, Ryan Powers, Lakshmipriyadarshini Satyabhama, Ang Cui, Christopher Tipton, Miri Michaeli, Ioanna Skountzou, Robert S Mittler, Steven H Kleinstein, Ramit Mehr, Frances Eun-Yun Lee, Ignacio Sanz, Joshy Jacob

Tetanus vaccination with a dissolving microneedle patch confers protective immune responses in pregnancy

使用可溶解微针贴片接种破伤风疫苗可在怀孕期间产生保护性免疫反应

E Stein Esser, AndreyA Romanyuk, Elena V Vassilieva, Joshy Jacob, Mark R Prausnitz, Richard W Compans, Ioanna Skountzou

Programming the magnitude and persistence of antibody responses with innate immunity

利用先天免疫控制抗体反应的强度和持久性

Sudhir Pai Kasturi, Ioanna Skountzou, Randy A Albrecht, Dimitrios Koutsonanos, Tang Hua, Helder I Nakaya, Rajesh Ravindran, Shelley Stewart, Munir Alam, Marcin Kwissa, Francois Villinger, Niren Murthy, John Steel, Joshy Jacob, Robert J Hogan, Adolfo García-Sastre, Richard Compans, Bali Pulendran

Perfusion fixation preserves enhanced yellow fluorescent protein and other cellular markers in lymphoid tissues

灌注固定可保留淋巴组织中的增强型黄色荧光蛋白和其他细胞标记物

Joseph G Dauner, Craig P Chappell, Ifor R Williams, Joshy Jacob