日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting cannabinoid receptor 1 for antagonism in pro-fibrotic alveolar macrophages mitigates pulmonary fibrosis

靶向拮抗促纤维化肺泡巨噬细胞中的大麻素受体1可减轻肺纤维化

Basu, Abhishek; Arif, Muhammad; Wolf, Kaelin M; Behee, Madeline; Johnson, Natalie; Pommerolle, Lenny; Pineda, Ricardo H; Sembrat, John; Zawatsky, Charles N; Dvorácskó, Szabolcs; Coffey, Nathan J; Park, Joshua K; Karagoz, Seray B; Godlewski, Grzegorz; Jourdan, Tony; Harvey-White, Judith; Königshoff, Melanie; Iyer, Malliga R; Cinar, Resat

A Simplified and Robust Model for the Study of Diabetic Nephropathy: Streptozotocin-Induced Diabetic Mice Fed a High-Protein Diet.

用于研究糖尿病肾病的简化而稳健的模型:链脲佐菌素诱导的糖尿病小鼠喂食高蛋白饮食

Pointeau Océane, Barbosa Romain, Loriot Maéva, Leemput Julia, Dubus Elisabeth, Causse Sébastien Zwe, Demizieux Laurent, Passilly-Degrace Patricia, Degrace Pascal, Vergès Bruno, Jourdan Tony

Inhibition of mitochondrial fatty acid β-oxidation activates mTORC1 pathway and protein synthesis via Gcn5-dependent acetylation of Raptor in zebrafish

抑制线粒体脂肪酸β-氧化可通过斑马鱼中Gcn5依赖的Raptor乙酰化激活mTORC1通路和蛋白质合成。

Zhou, Wen-Hao; Luo, Yuan; Li, Rui-Xin; Degrace, Pascal; Jourdan, Tony; Qiao, Fang; Chen, Li-Qiao; Zhang, Mei-Ling; Du, Zhen-Yu

Therapeutic potential of a novel peripherally restricted CB1R inverse agonist on the progression of diabetic nephropathy.

一种新型外周限制性 CB1R 反向激动剂对糖尿病肾病进展的治疗潜力

Jacquot Laetitia, Pointeau Océane, Roger-Villeboeuf Célia, Passilly-Degrace Patricia, Belkaid Rim, Regazzoni Isaline, Leemput Julia, Buch Chloé, Demizieux Laurent, Vergès Bruno, Degrace Pascal, Crater Glenn, Jourdan Tony

Do endocannabinoids acting via hepatic CB-1 contribute to NAFLD and hepatic insulin resistance?

内源性大麻素通过肝脏 CB-1 受体发挥作用是否会导致非酒精性脂肪性肝病和肝脏胰岛素抵抗?

Kunos, George; Jourdan, Tony; Tam, Joseph

Editorial: Immune Regulation of Metabolic Homeostasis

社论:代谢稳态的免疫调节

Guigas, Bruno; Jourdan, Tony; Stienstra, Rinke

Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasing de novo synthesis of long-chain ceramides

肝脏大麻素-1受体通过增加长链神经酰胺的从头合成来介导饮食诱导的胰岛素抵抗。

Cinar, Resat; Godlewski, Grzegorz; Liu, Jie; Tam, Joseph; Jourdan, Tony; Mukhopadhyay, Bani; Harvey-White, Judith; Kunos, George

Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy

足细胞中大麻素1受体过度活跃是2型糖尿病肾病的主要驱动因素。

Jourdan, Tony; Szanda, Gergő; Rosenberg, Avi Z; Tam, Joseph; Earley, Brian James; Godlewski, Grzegorz; Cinar, Resat; Liu, Ziyi; Liu, Jie; Ju, Cynthia; Pacher, Pál; Kunos, George

Role of adiponectin in the metabolic effects of cannabinoid type 1 receptor blockade in mice with diet-induced obesity

脂联素在饮食诱导肥胖小鼠中大麻素1型受体阻断的代谢效应中的作用

Tam, Joseph; Godlewski, Grzegorz; Earley, Brian J; Zhou, Liang; Jourdan, Tony; Szanda, Gergö; Cinar, Resat; Kunos, George

Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance

外周大麻素-1受体反向激动剂通过逆转瘦素抵抗来减轻肥胖

Tam, Joseph; Cinar, Resat; Liu, Jie; Godlewski, Grzegorz; Wesley, Daniel; Jourdan, Tony; Szanda, Gergő; Mukhopadhyay, Bani; Chedester, Lee; Liow, Jeih-San; Innis, Robert B; Cheng, Kejun; Rice, Kenner C; Deschamps, Jeffrey R; Chorvat, Robert J; McElroy, John F; Kunos, George