日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structure-Guided Optimization of Selective Covalent Reversible Peptidomimetic Inhibitors Targeting TMPRSS6

结构导向的TMPRSS6选择性共价可逆肽模拟抑制剂的优化

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c01998
Guerrab, Walid; Lepage, Matthieu; Désilets, Antoine; Joushomme, Alexandre; Desgagné, Michael; Froehlich, Ulrike; Leduc, Richard; Boudreault, Pierre-Luc
发表日期：2025
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From N-0385 to N-0920: Unveiling a Host-Directed Protease Inhibitor with Picomolar Antiviral Efficacy against Prevalent SARS-CoV-2 Variants.

从 N-0385 到 N-0920：揭示了一种宿主导向的蛋白酶抑制剂，对流行的 SARS-CoV-2 变种具有皮摩尔级的抗病毒功效

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.4c02468
Lemieux Gabriel, Pérez-Vargas Jimena, Désilets Antoine, Hassanzadeh Malihe, Thompson Connor A H, Gravel-Trudeau Alice, Joushomme Alexandre, Ennis Siobhan, Villanueva Ivan, Marouseau Étienne, Fraser Bryan J, Champagne William, Lepage Matthieu, Niikura Masahiro, Arrowsmith Cheryl H, Jean François, Leduc Richard, Boudreault Pierre-Luc
炎症/感染
新冠
Viral
发表日期：2025
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Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency

开发具有低纳摩尔效力的酮苯并噻唑类肽模拟TMPRSS13抑制剂

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2025.2466841
Joushomme, Alexandre; Désilets, Antoine; Champagne, William; Hassanzadeh, Malihe; Lemieux, Gabriel; Gravel-Trudeau, Alice; Lepage, Matthieu; Lafrenière, Sabrina; Froehlich, Ulrike; List, Karin; Boudreault, Pierre-Luc; Leduc, Richard
发表日期：2025
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