The myeloid SRC family kinase HCK regulates breast cancer growth by activating tumor-associated macrophage-led invasion and inhibiting cytotoxic T cell activity
髓系SRC家族激酶HCK通过激活肿瘤相关巨噬细胞介导的侵袭和抑制细胞毒性T细胞活性来调控乳腺癌的生长。
期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2026.1709102
Murrey, Michael W; Poh, Ashleigh R; Steer, James H; Rinaldi, Catherine; Mouchemore, Kellie A; Dwyer, Amy R; Denisenko, Elena; Kuznetsova, Irina; Yeow, Yen; Jones, Matthew E; Hmon, Khaing P W; Muirí, Dáithí Ó; Liu, Ya-Yu; Lin, Weitao; Forrest, Alistair R R; Ellies, Lesley G; Joyce, David A; Ernst, Matthias; Pixley, Fiona J
巨噬细胞
肿瘤
T细胞
HCK
肿瘤免疫
巨噬细胞
信号转导
SRC
乳腺癌
T细胞
细胞生物学
毒理研究
免疫/内分泌
