文献库，生知库 | 链接生命科学的每一步

日期影响因子

NPASS database update 2026: comprehensive quantitative composition, bioactivity, and ADME-Tox data of natural products for biomedical research

NPASS数据库2026年更新：用于生物医学研究的天然产物的全面定量组成、生物活性和ADME-Tox数据

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkaf1196

Lin, Hanbo; Hou, Dongyue; Jiang, Xianhan; Yin, Ruining; Yu, Shuntao; Lu, Songlin; Wang, Shanshan; Ju, Dianwen; Zhao, Hui; Chen, Yuzong; Zeng, Xian

发表日期：2026

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Nanobody-engineered bispecific IL-18 mimetics drive antitumor immunity by engaging CD8(+) T cell and evading IL-18BP in preclinical models.

纳米抗体工程化的双特异性 IL-18 模拟物通过与 CD8(+) T 细胞结合并逃避 IL-18BP，在临床前模型中驱动抗肿瘤免疫。

期刊:Molecular Therapy

影响因子:12

doi:10.1016/j.ymthe.2025.07.004

Nan Yanyang, Zhu Min, Wang Qian, Du Xiaoxue, Xu Caili, Huang Yuping, Liu Yujie, Zhou Shaoyuan, Qiu Yuluoyan, Chu Xiao, Ju Dianwen, Wan Yakun, Zhang Xuyao

细胞生物学

免疫/内分泌

发表日期：2025

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IL-2-loaded liposomes modified with sorafenib derivative exert a synergistic anti-melanoma effect via improving tumor immune microenvironment and enhancing antiangiogenic activity.

负载IL-2并用索拉非尼衍生物修饰的脂质体通过改善肿瘤免疫微环境和增强抗血管生成活性发挥协同抗黑色素瘤作用

期刊:Asian Journal of Pharmaceutical Sciences

影响因子:11.9

doi:10.1016/j.ajps.2025.101020

Huang Xuan, Kuerban Kudelaidi, Fan Jajun, Pan Danjie, Chen Huaning, Liu Jiayang, Wang Songna, Ju Dianwen, Zhu Yi Zhun, Liu Jiyong, Ye Li

发表日期：2025

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DDR1 Drives Collagen Remodeling and Immune Exclusion: Pan-Cancer Insights and Therapeutic Targeting in Pancreatic Ductal Adenocarcinoma

DDR1驱动胶原蛋白重塑和免疫排斥：胰腺导管腺癌的泛癌见解和治疗靶点

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26167731

Huang, Xuan; Jing, Guangjun; Kuerban, Kudelaidi; Fan, Jiajun; Yu, Mei; Yang, Shanglin; Chen, Wei; Huang, Litao; Ju, Dianwen; Zhu, Yi Zhun; Ye, Li

免疫/内分泌

发表日期：2025

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MiRNA-based drugs: challenges and delivery strategies

基于miRNA的药物：挑战与递送策略

期刊:Applied Microbiology and Biotechnology

影响因子:4.3

doi:10.1007/s00253-025-13620-0

Wang, Ziyu; Peng, Yingyuan; Zhou, Haifeng; Zhang, Min; Ju, Dianwen; Chen, Zhilong

发表日期：2025

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CMAUP database update 2024: extended functional and association information of useful plants for biomedical research

CMAUP数据库2024年更新：扩展了对生物医学研究有用的植物的功能和关联信息

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkad921

Hou, Dongyue; Lin, Hanbo; Feng, Yuhan; Zhou, Kaicheng; Li, Xingxiu; Yang, Yuan; Wang, Shuaiqi; Yang, Xue; Wang, Jiayu; Zhao, Hui; Zhang, Xuyao; Fan, Jiajun; Lu, SongLin; Wang, Dan; Zhu, Lyuhan; Ju, Dianwen; Chen, Yu Zong; Zeng, Xian

发表日期：2024

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Natural killer cell engagers: From bi-specific to tri-specific and tetra-specific engagers for enhanced cancer immunotherapy

自然杀伤细胞衔接器：从双特异性到三特异性和四特异性衔接器，用于增强癌症免疫疗法

期刊:Clinical and Translational Medicine

影响因子:6.8

doi:10.1002/ctm2.70046

Zhu, An; Bai, Yu; Nan, Yanyang; Ju, Dianwen

自然杀伤细胞

细胞生物学

免疫/内分泌

发表日期：2024

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Mechanisms and Clinical Implications of Human Gut Microbiota-Drug Interactions in the Precision Medicine Era

精准医疗时代人类肠道菌群与药物相互作用的机制及临床意义

期刊:Biomedicines

影响因子:3.9

doi:10.3390/biomedicines12010194

Wang, Shuaiqi; Ju, Dianwen; Zeng, Xian

发表日期：2024

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NPASS database update 2023: quantitative natural product activity and species source database for biomedical research

NPASS数据库2023年更新：用于生物医学研究的定量天然产物活性和物种来源数据库

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkac1069

Zhao, Hui; Yang, Yuan; Wang, Shuaiqi; Yang, Xue; Zhou, Kaicheng; Xu, Caili; Zhang, Xuyao; Fan, Jiajun; Hou, Dongyue; Li, Xingxiu; Lin, Hanbo; Tan, Ying; Wang, Shanshan; Chu, Xin-Yi; Zhuoma, Dongzhi; Zhang, Fengying; Ju, Dianwen; Zeng, Xian; Chen, Yu Zong

发表日期：2023

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Correction: Targeting the autophagy promoted antitumor effect of T-DM1 on HER2-positive gastric cancer

更正：靶向自噬促进T-DM1对HER2阳性胃癌的抗肿瘤作用

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/s41419-023-06061-y

Zhang, Jinghui; Fan, Jiajun; Zeng, Xian; Nie, Mingming; Chen, Wei; Wang, Yichen; Luan, Jingyun; Zhu, Zeguo; Chang, Xusheng; Ju, Dianwen; Feng, Li; Yin, Kai

发表日期：2023

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