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Ischemic Conditioning Promotes Transneuronal Survival and Stroke Recovery via CD36-Mediated Efferocytosis

缺血预适应通过 CD36 介导的胞吞作用促进跨神经元存活和中风恢复

doi:10.1161/CIRCRESAHA.124.325428

Ju, Hyunwoo; Kim, Il-Doo; Pavlova, Ina; Mu, Shang; Park, Keun Woo; Minkler, Joseph; Madkoor, Ahmed; Wang, Wei; Wang, Xiaoman; Wu, Zhuhao; Yang, Jiwon; Febbraio, Maria; Cave, John W; Cho, Sunghee

Acute, not delayed, treatment of aflibercept enhances vessel density in post-ischemic brain and promotes long-term stroke recovery in obese mice.

急性期而非延迟期使用阿柏西普治疗可提高缺血后脑血管密度，并促进肥胖小鼠中风后的长期恢复

期刊:Journal of Cerebral Blood Flow and Metabolism

影响因子:4.5

doi:10.1177/0271678X251330102

Ju Hyunwoo, Minker Joseph, Pavlova Ina, Cho Sunghee, Kim Il-Doo

Obesity-induced Ly6C(High) and Ly6C(Low) monocyte subset changes abolish post-ischemic limb conditioning benefits in stroke recovery

肥胖引起的Ly6C(高表达)和Ly6C(低表达)单核细胞亚群变化会消除缺血后肢体功能训练对中风恢复的益处

期刊:Journal of Cerebral Blood Flow and Metabolism

影响因子:4.5

doi:10.1177/0271678X231215101

Kim, Il-Doo; Ju, Hyunwoo; Minkler, Joseph; Madkoor, Ahmed; Park, Keun Woo; Cho, Sunghee

Endothelial cell CD36 mediates stroke-induced brain injury via BBB dysfunction and monocyte infiltration in normal and obese conditions

内皮细胞CD36通过血脑屏障功能障碍和单核细胞浸润介导正常和肥胖状态下的卒中诱导的脑损伤。

期刊:Journal of Cerebral Blood Flow and Metabolism

影响因子:4.5

doi:10.1177/0271678X231154602

Kim, Il-Doo; Ju, Hyunwoo; Minkler, Joseph; Jiang, Roselyn; Singh, Abhilasha; Sharma, Roopa; Febbraio, Maria; Cho, Sunghee

Conessine Interferes with Oxidative Stress-Induced C2C12 Myoblast Cell Death through Inhibition of Autophagic Flux.

康宁通过抑制自噬流干扰氧化应激诱导的 C2C12 成肌细胞死亡

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0157096

Kim Hyunju, Lee Kang Il, Jang Minsu, Namkoong Sim, Park Rackhyun, Ju Hyunwoo, Choi Inho, Oh Won Keun, Park Junsoo

Efferocytosis: Gateway for tissue resolution

胞吞作用：组织修复的途径

Ischemic Conditioning Promotes Transneuronal Survival and Stroke Recovery via CD36-Mediated Efferocytosis

缺血预适应通过 CD36 介导的胞吞作用促进跨神经元存活和中风恢复

Acute, not delayed, treatment of aflibercept enhances vessel density in post-ischemic brain and promotes long-term stroke recovery in obese mice.

急性期而非延迟期使用阿柏西普治疗可提高缺血后脑血管密度，并促进肥胖小鼠中风后的长期恢复

Obesity-induced Ly6C(High) and Ly6C(Low) monocyte subset changes abolish post-ischemic limb conditioning benefits in stroke recovery

肥胖引起的Ly6C(高表达)和Ly6C(低表达)单核细胞亚群变化会消除缺血后肢体功能训练对中风恢复的益处

Endothelial cell CD36 mediates stroke-induced brain injury via BBB dysfunction and monocyte infiltration in normal and obese conditions

内皮细胞CD36通过血脑屏障功能障碍和单核细胞浸润介导正常和肥胖状态下的卒中诱导的脑损伤。

Conessine Interferes with Oxidative Stress-Induced C2C12 Myoblast Cell Death through Inhibition of Autophagic Flux.

康宁通过抑制自噬流干扰氧化应激诱导的 C2C12 成肌细胞死亡