日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CAR-engineered lymphocyte persistence is governed by a FAS ligand-FAS autoregulatory circuit

CAR工程化淋巴细胞的持久性受FAS配体-FAS自身调节回路的调控。

Fei Yi,Tal Cohen,Natalie Zimmerman,Friederike Dündar,Paul Zumbo,Razan Eltilib,Erica J Brophy,Hannah Arkin,Judith Feucht,Michael V Gormally,Christopher S Hackett,Korbinian N Kropp,Inaki Etxeberria,Smita S Chandran,Zeguo Zhao,Winson Cai,Anthony F Daniyan,Jae H Park,Caleb A Lareau,Katharine C Hsu,Michel Sadelain,Doron Betel,Christopher A Klebanoff

Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease

胃癌体细胞小鼠模型揭示了转移性疾病的基因型特异性特征

Josef Leibold # ,Kaloyan M Tsanov # ,Corina Amor # ,Yu-Jui Ho ,Francisco J Sánchez-Rivera ,Judith Feucht ,Timour Baslan ,Hsuan-An Chen ,Sha Tian ,Janelle Simon ,Alexandra Wuest ,John E Wilkinson ,Scott W Lowe

CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit

CAR 工程淋巴细胞持久性受 FAS 配体/FAS 自调节回路控制

Fei Yi, Tal Cohen, Natalie Zimmerman, Friederike Dündar, Paul Zumbo, Razan Eltilib, Erica J Brophy, Hannah Arkin, Judith Feucht, Michael V Gormally, Christopher S Hackett, Korbinian N Kropp, Inaki Etxeberria, Smita S Chandran, Jae H Park, Katharine C Hsu, Michel Sadelain, Doron Betel, Christopher A

TET2 guards against unchecked BATF3-induced CAR T cell expansion

TET2 防止不受控制的 BATF3 诱导的 CAR T 细胞扩增

Nayan Jain #, Zeguo Zhao #, Judith Feucht, Richard Koche, Archana Iyer, Anton Dobrin, Jorge Mansilla-Soto, Julie Yang, Yingqian Zhan, Michael Lopez, Gertrude Gunset, Michel Sadelain

HLA-independent T cell receptors for targeting tumors with low antigen density

用于靶向低抗原密度肿瘤的HLA非依赖性T细胞受体

Jorge Mansilla-Soto # ,Justin Eyquem # ,Sascha Haubner ,Mohamad Hamieh ,Judith Feucht ,Noémie Paillon ,Andrés Ernesto Zucchetti ,Zhuoning Li ,Maria Sjöstrand ,Pieter L Lindenbergh ,Michelle Saetersmoen ,Anton Dobrin ,Mathieu Maurin ,Archana Iyer ,Andreina Garcia Angus ,Matthew M Miele ,Zeguo Zhao ,Theodoros Giavridis ,Sjoukje J C van der Stegen ,Fella Tamzalit ,Isabelle Rivière ,Morgan Huse ,Ronald C Hendrickson ,Claire Hivroz ,Michel Sadelain

The oncogenic fusion protein DNAJB1-PRKACA can be specifically targeted by peptide-based immunotherapy in fibrolamellar hepatocellular carcinoma

在纤维板层型肝细胞癌中,致癌融合蛋白DNAJB1-PRKACA可作为基于肽的免疫疗法的特异性靶点。

Jens Bauer ,Natalie Köhler ,Yacine Maringer ,Philip Bucher ,Tatjana Bilich ,Melissa Zwick ,Severin Dicks ,Annika Nelde ,Marissa Dubbelaar ,Jonas Scheid ,Marcel Wacker ,Jonas S Heitmann ,Sarah Schroeder ,Jonas Rieth ,Monika Denk ,Marion Richter ,Reinhild Klein ,Irina Bonzheim ,Julia Luibrand ,Ursula Holzer ,Martin Ebinger ,Ines B Brecht ,Michael Bitzer ,Melanie Boerries ,Judith Feucht ,Helmut R Salih ,Hans-Georg Rammensee ,Stephan Hailfinger ,Juliane S Walz

Protective T cell receptor identification for orthotopic reprogramming of immunity in refractory virus infections

保护性 T 细胞受体识别,用于难治性病毒感染中的原位免疫重编程

Tanja A Stief, Theresa Kaeuferle, Thomas R Müller, Michaela Döring, Lena M Jablonowski, Kilian Schober, Judith Feucht, Kevin M Dennehy, Semjon Willier, Franziska Blaeschke, Rupert Handgretinger, Peter Lang, Dirk H Busch, Tobias Feuchtinger

Senolytic CAR T cells reverse senescence-associated pathologies

衰老细胞清除型CAR-T细胞逆转衰老相关病理

Corina Amor # ,Judith Feucht # ,Josef Leibold # ,Yu-Jui Ho ,Changyu Zhu ,Direna Alonso-Curbelo ,Jorge Mansilla-Soto ,Jacob A Boyer ,Xiang Li ,Theodoros Giavridis ,Amanda Kulick ,Shauna Houlihan ,Ellinor Peerschke ,Scott L Friedman ,Vladimir Ponomarev ,Alessandra Piersigilli ,Michel Sadelain ,Scott W Lowe

Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis

小鼠模型中的体细胞组织工程揭示了 WNT 通路改变在前列腺癌转移中的可操作作用

Josef Leibold #, Marcus Ruscetti #, Zhen Cao #, Yu-Jui Ho, Timour Baslan, Min Zou, Wassim Abida, Judith Feucht, Teng Han, Francisco M Barriga, Kaloyan M Tsanov, Leah Zamechek, Amanda Kulick, Corina Amor, Sha Tian, Katarzyna Rybczyk, Nelson R Salgado, Francisco J Sánchez-Rivera, Philip A Watson, Elis

Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency

CAR激活潜能的校准决定了T细胞的不同命运和治疗效力。

Judith Feucht #,Jie Sun #,Justin Eyquem,Yu-Jui Ho,Zeguo Zhao,Josef Leibold,Anton Dobrin,Annalisa Cabriolu,Mohamad Hamieh,Michel Sadelain