日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multi-omic network analysis identified betacellulin as a novel target of omega-3 fatty acid attenuation of western diet-induced nonalcoholic steatohepatitis.

多组学网络分析发现β细胞素是ω-3脂肪酸减弱西方饮食诱发的非酒精性脂肪性肝炎的新靶点

Padiadpu Jyothi, Garcia-Jaramillo Manuel, Newman Nolan K, Pederson Jacob W, Rodrigues Richard, Li Zhipeng, Singh Sehajvir, Monnier Philip, Trinchieri Giorgio, Brown Kevin, Dzutsev Amiran K, Shulzhenko Natalia, Jump Donald B, Morgun Andrey

Early transcriptome changes associated with western diet induced NASH in Ldlr(-/-) mice points to activation of hepatic macrophages and an acute phase response

在Ldlr(-/-)小鼠中,与高脂饮食诱导的非酒精性脂肪性肝炎(NASH)相关的早期转录组变化表明肝巨噬细胞被激活并引发急性期反应。

Padiadpu, Jyothi; Spooner, Melinda H; Li, Zhipeng; Newman, Nolan; Löhr, Christiane V; Apperson, K Denise; Dzutsev, Amiran; Trinchieri, Giorgio; Shulzhenko, Natalia; Morgun, Andrey; Jump, Donald B

Time course of western diet (WD) induced nonalcoholic steatohepatitis (NASH) in female and male Ldlr-/- mice

在雌性和雄性Ldlr-/-小鼠中,西方饮食(WD)诱导的非酒精性脂肪性肝炎(NASH)的时间进程

Spooner, Melinda H; Garcia-Jaramillo, Manuel; Apperson, K Denise; Löhr, Christiane V; Jump, Donald B

Role of gut microbiota in type 2 diabetes pathophysiology

肠道菌群在2型糖尿病病理生理学中的作用

Gurung, Manoj; Li, Zhipeng; You, Hannah; Rodrigues, Richard; Jump, Donald B; Morgun, Andrey; Shulzhenko, Natalia

Omega-3 fatty acids and nonalcoholic fatty liver disease in adults and children: where do we stand?

Omega-3 脂肪酸与成人和儿童非酒精性脂肪肝疾病:我们目前的研究进展如何?

Spooner, Melinda H; Jump, Donald B

Thermoneutral housing attenuates premature cancellous bone loss in male C57BL/6J mice.

热中性饲养可减轻雄性 C57BL/6J 小鼠过早的松质骨丢失

Martin Stephen A, Philbrick Kenneth A, Wong Carmen P, Olson Dawn A, Branscum Adam J, Jump Donald B, Marik Charles K, DenHerder Jonathan M, Sargent Jennifer L, Turner Russell T, Iwaniec Urszula T

Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice.

二十二碳六烯酸可阻止肥胖 Ldlr-/- 小鼠中由西方饮食引起的非酒精性脂肪性肝炎的进展

Lytle Kelli A, Wong Carmen P, Jump Donald B

Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer

膳食ω-3脂肪酸具有预防非酒精性脂肪肝和降低原发性肝癌风险的潜力

Jump, Donald B; Depner, Christopher M; Tripathy, Sasmita; Lytle, Kelli A

Docosahexaenoic acid attenuates Western diet-induced hepatic fibrosis in Ldlr-/- mice by targeting the TGFβ-Smad3 pathway.

二十二碳六烯酸通过靶向 TGFβ-Smad3 通路减轻 Ldlr-/- 小鼠中西方饮食引起的肝纤维化

Lytle Kelli A, Depner Christopher M, Wong Carmen P, Jump Donald B

Novel liquid chromatography-mass spectrometry method shows that vitamin E deficiency depletes arachidonic and docosahexaenoic acids in zebrafish (Danio rerio) embryos

一种新型液相色谱-质谱联用方法表明,维生素E缺乏会导致斑马鱼(Danio rerio)胚胎中花生四烯酸和二十二碳六烯酸的含量降低。

Lebold, Katie M; Kirkwood, Jay S; Taylor, Alan W; Choi, Jaewoo; Barton, Carrie L; Miller, Galen W; La Du, Jane; Jump, Donald B; Stevens, Jan Frederik; Tanguay, Robert L; Traber, Maret G