文献库，生知库 | 链接生命科学的每一步

Single-Cell Lineage Trajectory Defines Cyclin-Dependent Kinase Inhibitor-Sensitive Cells-of-Origin in Esophageal Squamous Cell Carcinoma

单细胞谱系轨迹定义了食管鳞状细胞癌中对细胞周期蛋白依赖性激酶抑制剂敏感的起源细胞

期刊:Gastro Hep Advances

影响因子:

doi:10.1016/j.gastha.2025.100874

Ko, Kyung-Pil; Zhang, Jie; Jun, Sohee; Park, Jae-Il

Deciphering precursor cell dynamics in esophageal preneoplasia via genetic barcoding and single-cell transcriptomics

利用基因条形码和单细胞转录组学解析食管癌前病变中前体细胞的动态变化

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2509534122

Jang, Jinho; Ko, Kyung-Pil; Zhang, Jie; Jun, Sohee; Park, Jae-Il

Actin dysregulation induces neuroendocrine plasticity and immune evasion: a vulnerability of small cell lung cancer

肌动蛋白失调诱导神经内分泌可塑性和免疫逃逸：小细胞肺癌的脆弱性

期刊:Nature Communications

影响因子:

doi:10.1038/s41467-025-67078-9

Seo, Yoojeong; Zhang, Shengzhe; Jang, Jinho; Ko, Kyung-Pil; Kim, Kee-Beom; Huang, Yuanjian; Kim, Dong-Wook; Kim, Bongjun; Zou, Gengyi; Zhang, Jie; Jun, Sohee; Chu, Wonhong; Kirk, Nicole A; Hwang, Ye Eun; Ban, Young Ho; Dhar, Shilpa S; Chan, Joseph M; Lee, Min Gyu; Rudin, Charles M; Park, Kwon-Sik; Park, Jae-Il

Deciphering Precursor Cell Dynamics in Esophageal Preneoplasia via Genetic Barcoding and Single-Cell Transcriptomics.

利用基因条形码和单细胞转录组学破译食管癌前病变中的前体细胞动力学。

期刊:

影响因子:

doi:10.1101/2025.02.26.637920

Jang Jinho, Ko Kyung-Pil, Zhang Jie, Jun Sohee, Park Jae-Il

Tumor niche network-defined subtypes predict immunotherapy response of esophageal squamous cell cancer

肿瘤微环境网络定义的亚型可预测食管鳞状细胞癌的免疫治疗反应

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2024.109795

Ko, Kyung-Pil; Zhang, Shengzhe; Huang, Yuanjian; Kim, Bongjun; Zou, Gengyi; Jun, Sohee; Zhang, Jie; Zhao, Yahui; Martin, Cecilia; Dunbar, Karen J; Efe, Gizem; Rustgi, Anil K; Nakagawa, Hiroshi; Zhang, Haiyang; Liu, Zhihua; Park, Jae-Il

Actin dysregulation induces immune evasion via oxidative stress-activated PD-L1 in gastric cancer

肌动蛋白失调通过氧化应激激活的PD-L1诱导胃癌免疫逃逸

期刊:

影响因子:

doi:10.1101/2024.12.18.629227

Seo, Yoojeong; Jang, Jinho; Ko, Kyung-Pil; Zou, Gengyi; Huang, Yuanjian; Zhang, Shengzhe; Zhang, Jie; Jun, Sohee; Chu, Wonhong; Venkatesan, Vishwa; Dhakshinamoorthy, Sanjana; Park, Jae-Il

Key Genetic Determinants Driving Esophageal Squamous Cell Carcinoma Initiation and Immune Evasion

驱动食管鳞状细胞癌发生和免疫逃逸的关键遗传决定因素

期刊:Gastroenterology

影响因子:25.1

doi:10.1053/j.gastro.2023.05.030

Ko, Kyung-Pil; Huang, Yuanjian; Zhang, Shengzhe; Zou, Gengyi; Kim, Bongjun; Zhang, Jie; Jun, Sohee; Martin, Cecilia; Dunbar, Karen J; Efe, Gizem; Rustgi, Anil K; Nakagawa, Hiroshi; Park, Jae-Il

Lysosomal TMEM9-LAMTOR4-controlled mTOR signaling integrity is required for mammary tumorigenesis

溶酶体TMEM9-LAMTOR4控制的mTOR信号完整性是乳腺肿瘤发生所必需的

期刊:Cancer Communications

影响因子:24.9

doi:10.1002/cac2.12382

Zhang, Shengzhe; Lee, Sung Ho; Nie, Litong; Huang, Yuanjian; Zou, Gengyi; Jung, Youn-Sang; Jun, Sohee; Zhang, Jie; Lien, Esther M; Chen, Junjie; Park, Jae-Il

Tumor Niche Network-Defined Subtypes Predict Immunotherapy Response of Esophageal Squamous Cell Cancer

肿瘤微环境网络定义的亚型可预测食管鳞状细胞癌的免疫治疗反应

期刊:

影响因子:

doi:10.1101/2023.02.15.528539

Ko, Kyung-Pil; Zhang, Shengzhe; Huang, Yuanjian; Kim, Bongjun; Zou, Gengyi; Jun, Sohee; Zhang, Jie; Martin, Cecilia; Dunbar, Karen J; Efe, Gizem; Rustgi, Anil K; Zhang, Haiyang; Nakagawa, Hiroshi; Park, Jae-Il

NFATc3 Enhances DREAM Complex-Driven Transactivation

NFATc3 增强 DREAM 复合物驱动的转录激活

Single-Cell Lineage Trajectory Defines Cyclin-Dependent Kinase Inhibitor-Sensitive Cells-of-Origin in Esophageal Squamous Cell Carcinoma

单细胞谱系轨迹定义了食管鳞状细胞癌中对细胞周期蛋白依赖性激酶抑制剂敏感的起源细胞

Deciphering precursor cell dynamics in esophageal preneoplasia via genetic barcoding and single-cell transcriptomics

利用基因条形码和单细胞转录组学解析食管癌前病变中前体细胞的动态变化

Actin dysregulation induces neuroendocrine plasticity and immune evasion: a vulnerability of small cell lung cancer

肌动蛋白失调诱导神经内分泌可塑性和免疫逃逸：小细胞肺癌的脆弱性

Deciphering Precursor Cell Dynamics in Esophageal Preneoplasia via Genetic Barcoding and Single-Cell Transcriptomics.

利用基因条形码和单细胞转录组学破译食管癌前病变中的前体细胞动力学。

Tumor niche network-defined subtypes predict immunotherapy response of esophageal squamous cell cancer

肿瘤微环境网络定义的亚型可预测食管鳞状细胞癌的免疫治疗反应

Actin dysregulation induces immune evasion via oxidative stress-activated PD-L1 in gastric cancer

肌动蛋白失调通过氧化应激激活的PD-L1诱导胃癌免疫逃逸

Key Genetic Determinants Driving Esophageal Squamous Cell Carcinoma Initiation and Immune Evasion

驱动食管鳞状细胞癌发生和免疫逃逸的关键遗传决定因素

Lysosomal TMEM9-LAMTOR4-controlled mTOR signaling integrity is required for mammary tumorigenesis

溶酶体TMEM9-LAMTOR4控制的mTOR信号完整性是乳腺肿瘤发生所必需的

Tumor Niche Network-Defined Subtypes Predict Immunotherapy Response of Esophageal Squamous Cell Cancer

肿瘤微环境网络定义的亚型可预测食管鳞状细胞癌的免疫治疗反应