SIRT2-mediated deacetylation of LCK governs the magnitude of T cell receptor signaling.
SIRT2 介导的 LCK 去乙酰化控制着 T 细胞受体信号的强度。
期刊:Nature Immunology
影响因子:27.6
doi:10.1038/s41590-025-02377-3
Hamaidi Imene, Cheng Pingyan, Jun Soo Young, Manna Alak, Wang Min-Hsuan, Nguyen Anh, Can Ismail, Zhang Min G, Taylor Odesha O, Bailon Luis Uriel Lopez, Fang Bin, Perez Bradford, Creelan Ben C, Marusyk Andriy, Shin Dongjun, Hwang Tae Hyun, Berglund Anders E, Shapiro Virginia S, Ji Haitao M, Conejo-Garcia José R, Kim Sungjune
细胞生物学
LCK
SirT2
T Cell Receptor
乙酰化
