Autism-associated ARHGEF9 variants impair GABAergic synapses and ultrasonic communication by reducing gephyrin phosphorylation.
与自闭症相关的 ARHGEF9 变异体通过减少 gephyrin 磷酸化来损害 GABA 能突触和超声波通讯。
期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-025-03313-5
Jung Hyeji, Kim Byeongchan, Jang Gyubin, Lee Hyojung, Kim Younghye, Kim Hyeonho, Lee Hea Ji, Kim Dongwook, Yang Yeji, Jeong Woo Chan, Kim Seungjoon, Han Ah-Reum, Kim Ho Min, Papadopoulos Theofilos, Durand Benjamin, Francannet Christine, Piton Amélie, Kim Jin Young, Ko Jaewon, Um Ji Won
