Junmin Quan相关文献与解析，生知库 | 链接生命科学的每一步

Enhancing RNA-seq bias mitigation with the Gaussian self-benchmarking framework: towards unbiased sequencing data

利用高斯自基准测试框架增强RNA-seq偏差缓解：迈向无偏测序数据

期刊:BMC Genomics

影响因子:3.5

doi:10.1186/s12864-024-10814-0

Qiang Su # ,Yi Long # ,Deming Gou ,Junmin Quan ,Qizhou Lian

发表日期：2024

文献求助收藏

Feedback activation of CD73-Adenosine axis attenuates the antitumor immunity of STING pathway

CD73-腺苷轴的反馈激活减弱了STING通路的抗肿瘤免疫力

期刊:Biochemical and Biophysical Research Communications

影响因子:2.5

doi:10.1016/j.bbrc.2024.149814

Nannan Fu, Ziang Zhang, Junmin Quan

Cyclopeptide Inhibitors Target the N-Terminal Tail of STING and Alleviate Autoinflammation

环肽抑制剂靶向 STING 的 N 端尾部并缓解自身炎症

期刊:Chemistry & Biodiversity

影响因子:2.3

doi:10.1002/cbdv.202401253

Junmin Quan, Xiaoquan Wang, Anqi Cao, Wenlv Zheng

信号转导

发表日期：2024

文献求助收藏

Development of cyclopeptide inhibitors of cGAS targeting protein-DNA interaction and phase separation

针对蛋白质-DNA相互作用和相分离的cGAS环肽抑制剂的开发

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-023-41892-5

Xiaoquan Wang #, Youqiao Wang #, Anqi Cao, Qinhong Luo, Daoyuan Chen, Weiqi Zhao, Jun Xu, Qinkai Li, Xianzhang Bu, Junmin Quan

S-acylthioalkyl ester (SATE)-based prodrugs of deoxyribose cyclic dinucleotides (dCDNs) as the STING agonist for antitumor immunotherapy

基于 S-酰硫烷基酯 (SATE) 的脱氧核糖环二核苷酸 (dCDN) 前药作为抗肿瘤免疫治疗的 STING 激动剂

期刊:European Journal of Medicinal Chemistry

影响因子:6

doi:10.1016/j.ejmech.2022.114796

Zhiqiang Xie, Liqing Lu, Zhenghua Wang, Qinhong Luo, Yuchen Yang, Tian Fang, Ziyi Chen, Dejun Ma, Junmin Quan, Zhen Xi

肿瘤

发表日期：2022

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Biguanide MC001, a Dual Inhibitor of OXPHOS and Glycolysis, Shows Enhanced Antitumor Activity Without Increasing Lactate Production

双胍类 MC001 是 OXPHOS 和糖酵解的双重抑制剂，具有增强的抗肿瘤活性，且不会增加乳酸的产生

期刊:ChemMedChem

影响因子:3.6

doi:10.1002/cmdc.202100674

Jiamiao Fu, Siyu Liu, Minqiang Hu, Ximing Liao, Xiaoquan Wang, Zhengshuang Xu, Qinkai Li, Junmin Quan

肿瘤

发表日期：2022

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STAT3 inhibition enhances CDN-induced STING signaling and antitumor immunity

STAT3 抑制可增强 CDN 诱导的 STING 信号传导和抗肿瘤免疫

期刊:Cancer Letters

影响因子:9.1

doi:10.1016/j.canlet.2019.02.029

Jianwen Pei, Yibo Zhang, Qinhong Luo, Wenlv Zheng, Wanxuan Li, Xin Zeng, Qinkai Li, Junmin Quan

Structural basis for dimerization of the death effector domain of the F122A mutant of Caspase-8

Caspase-8 F122A 突变体死亡效应域二聚化的结构基础

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-018-35153-5

Chen Shen, Jianwen Pei, Xiaomin Guo, Lu Zhou, Qinkai Li, Junmin Quan

信号转导

发表日期：2018

文献求助收藏

Deep structural clustering reveals hidden systematic biases in RNA sequencing data

深度结构聚类揭示了RNA测序数据中隐藏的系统性偏差

A Novel HDAC6 Inhibitor Ameliorates Imiquimod-Induced Psoriasis-Like Inflammation in Mice

一种新型HDAC6抑制剂可减轻咪喹莫特诱导的小鼠银屑病样炎症

Enhancing RNA-seq bias mitigation with the Gaussian self-benchmarking framework: towards unbiased sequencing data

利用高斯自基准测试框架增强RNA-seq偏差缓解：迈向无偏测序数据

Feedback activation of CD73-Adenosine axis attenuates the antitumor immunity of STING pathway

CD73-腺苷轴的反馈激活减弱了STING通路的抗肿瘤免疫力

Cyclopeptide Inhibitors Target the N-Terminal Tail of STING and Alleviate Autoinflammation

环肽抑制剂靶向 STING 的 N 端尾部并缓解自身炎症

Development of cyclopeptide inhibitors of cGAS targeting protein-DNA interaction and phase separation

针对蛋白质-DNA相互作用和相分离的cGAS环肽抑制剂的开发

S-acylthioalkyl ester (SATE)-based prodrugs of deoxyribose cyclic dinucleotides (dCDNs) as the STING agonist for antitumor immunotherapy

基于 S-酰硫烷基酯 (SATE) 的脱氧核糖环二核苷酸 (dCDN) 前药作为抗肿瘤免疫治疗的 STING 激动剂

Biguanide MC001, a Dual Inhibitor of OXPHOS and Glycolysis, Shows Enhanced Antitumor Activity Without Increasing Lactate Production

双胍类 MC001 是 OXPHOS 和糖酵解的双重抑制剂，具有增强的抗肿瘤活性，且不会增加乳酸的产生

STAT3 inhibition enhances CDN-induced STING signaling and antitumor immunity

STAT3 抑制可增强 CDN 诱导的 STING 信号传导和抗肿瘤免疫

Structural basis for dimerization of the death effector domain of the F122A mutant of Caspase-8

Caspase-8 F122A 突变体死亡效应域二聚化的结构基础