日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Elebsiran and PEG-IFNα for chronic hepatitis B infection: a partially randomized, open-label, phase 2 trial

Elebsiran 和 PEG-IFNα 治疗慢性乙型肝炎感染：一项部分随机、开放标签的 II 期试验

期刊:Nature Medicine
影响因子:50
doi:10.1038/s41591-025-04049-z
Wong, Grace Lai-Hung; Yuen, Man-Fung; Lin, Bingliang; Douglas, Mark W; Hu, Peng; Xie, Qing; Lv, Fangfang; Tak, Won Young; Leerapun, Apinya; Kim, Dong Joon; Tangkijvanich, Pisit; Lim, Young-Suk; Dai, Chia-Yen; O'Beirne, James; Weltman, Martin; Khemnark, Suparat; Piratvisuth, Teerha; Manasirisuk, Witsarut; Chen, Xinyue; Liu, Chun-Jen; Heo, Jeong; Lee, Jooho; Niu, Junqi; Kumar, Rahul; Kumar, Rajneesh; Zhu, Chong; Cao, Ke; Tian, Alex; Chen, Xiaofei; Zhu, Qing; Margolis, David; Jia, Jidong; Hong, Zhi
炎症/感染
肝炎
发表日期：2026
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Integrating single cell- and spatial- resolved transcriptomics unravels the inter-tumor heterogeneity and immunosuppressive landscape in HBV- and Clonorchis sinensis-associated hepatocellular carcinoma.

整合单细胞和空间分辨转录组学，揭示了 HBV 和中华肝吸虫相关肝细胞癌的肿瘤间异质性和免疫抑制图谱。

期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-025-02381-z
Chen Jiayun, Lu Wenmin, Lou Yanni, Liu Jing, Liao Xiwen, Bai Yunmeng, Cheng Guangqing, Zhu Guangzhi, Feng Ji, Liu Junqi, Liu Zhaoji, Jia Liqun, Zhou Jing, Peng Tao, Lu Guo-Dong, Wang Jigang
肝癌
细胞生物学
单细胞
发表日期：2026
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Power-efficient ultra-broadband soliton microcombs in resonantly-coupled microresonators

谐振耦合微谐振器中的高效超宽带孤子微梳

期刊:Light-Science & Applications
影响因子:23.4
doi:10.1038/s41377-026-02186-9
Zhu, Kaixuan; Luo, Xinrui; Wang, Yuanlei; Wang, Ze; Xu, Tianyu; Qian, Du; Cheng, Yinke; Wang, Junqi; Luo, Haoyang; Liu, Yanwu; Jin, Xing; Xie, Zhenyu; Zhou, Xin; Wang, Min; Liu, Jian-Fei; Cao, Xuening; Wang, Ting; Tang, Shui-Jing; Gong, Qihuang; Li, Bei-Bei; Yang, Qi-Fan
发表日期：2026
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Mechanically compliant and cost-effective 1.4Li(2)O-0.75ZrCl(4)-0.25AlCl(3) solid electrolyte for all-solid-state batteries with improved cycling stability

一种机械性能良好且经济高效的1.4Li₂O-0.75ZrCl₄-0.25AlCl₃固体电解质，适用于具有改进循环稳定性的全固态电池。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-68210-5
Hu, Lv; He, Yaolong; Wang, Dong; Li, Wanxia; Yao, Jingming; Zhang, Xiaolong; Zhu, Jinfeng; Chen, Huaican; Yin, Wen; Wang, Yanru; Yan, Kejun; Wang, Jinzhu; Li, Hui; Chen, Fang; Liu, Yating; Lai, Junqi; Chen, Qi; Ma, Jie; Jiao, Shuhong; Wang, Guorui; Shi, Siqi; Chen, Liwei; Huang, Jianyu; Ma, Cheng
发表日期：2026
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PDZK1-ULK1 Axis Triggers Lipophagy to Inhibit Tumor Progression and Sunitinib Resistance in Clear Cell Renal Cell Carcinoma

PDZK1-ULK1轴触发脂质自噬以抑制透明细胞肾细胞癌的肿瘤进展和舒尼替尼耐药性

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202511606
Qi, Xuan; Guo, Yu; Yang, Yumeng; Wang, Haibo; Yang, Xiaomei; Song, Ran; Qin, Qiong; Zhang, Yan; Hu, Meihan; Zhou, Haixing; Feng, Duiping; He, Junqi
肿瘤
肿瘤免疫
ULK1
肾癌
细胞生物学
自噬
发表日期：2026
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ERM Inhibition Confers Ferroptosis Resistance through ROS-Induced NRF2 Signaling.

ERM抑制通过ROS诱导的NRF2信号传导赋予铁死亡抵抗力。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202513310
Qiao Menghao, Zhou Liqun, Zhou Minhua, Fang Yu, Mai Haiying, Cao Lingbo, Xu Kun, Sang Yuan, Chen Minyi, Huang Jiewei, Huang Peiyi, Yan Zhipeng, Wang Chao, Dai Zhangshuai, Huang Dichun, He Ronghan, Pang Lijuan, Guo Yunmiao, Chew Ting Gang, Huang Junqi
信号转导
NRF2
铁死亡
发表日期：2026
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Micro-Organ Chip Deciphers Tumor-Derived G-CSF as Remote Commander of Lung Pre-Metastatic Niche via VEGFA-KDR Cascade.

微型器官芯片揭示肿瘤来源的 G-CSF 通过 VEGFA-KDR 级联反应远程调控肺部转移前微环境。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202518584
Zhang Jingxin, Huang Xiaoying, Ma Lingchuan, Chen Zixing, Li Tianyao, Wang Lijian, Guo Yutong, Xu Hu, Li Junqi, Qin Jiang-Jiang, Wang Xiang, Cao Yuhong, Miao Kai
肺癌
肿瘤
EGF
KDR
VEGF
VEGFA
G-CSF
器官芯片
发表日期：2026
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Sono-piezoelectric cues regulate neuroinflammatory reflex-arc-mediated α7nAChR-P2RX7 axis to dampen osteoarthritis-correlated pain with osteoarthritis attenuation

声压电信号调节神经炎症反射弧介导的α7nAChR-P2RX7轴，从而减轻骨关节炎相关疼痛并缓解骨关节炎症状。

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.125686
Zhong, Qiuling; Xie, Junqi; Zuo, Maocheng; Liao, Chuanan; Peng, Qiuxia; Yu, Simeng; Hu, Pan; Liu, Yuanyuan; Zheng, Li; Zhang, Kun; Lu, Zhenhui; Zhao, Jinmin
炎症
炎症/感染
信号转导
AChR
神经科学
关节炎
神经炎症
发表日期：2026
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Biomimetic ECM collagen hydrogel induces chondrogenic differentiation of BMSCs by activating autophagy through POU5F1-mediated AMPK/mTOR signaling pathway

仿生细胞外基质胶原水凝胶通过POU5F1介导的AMPK/mTOR信号通路激活自噬，诱导骨髓间充质干细胞向软骨细胞分化。

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.126710
Ru, Xiao; Yu, Zhongwen; Li, Jun; Xu, Fuben; Xu, Guojie; Xie, Junqi; Yu, Simeng; Hu, Pan; Liu, YuanYuan; Zheng, Li; Zhao, Jinmin; Lu, Zhenhui
发育与干细胞
mTOR
信号转导
AMPK
干细胞
细胞生物学
自噬
发表日期：2026
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Correction: Transdermal delivery of CRISPR/Cas9-mediated melanoma gene therapy via polyamines-modified thermosensitive hydrogels

更正：通过聚胺修饰的热敏水凝胶进行CRISPR/Cas9介导的黑色素瘤基因治疗的透皮递送

期刊:Journal of Nanobiotechnology
影响因子:12.6
doi:10.1186/s12951-026-04247-y
Li, Meng; Zhou, Songli; Zhang, Suqin; Xie, Xingyu; Nie, Junqi; Wang, Qi; Ma, Lixin; Cheng, Yibin; Luo, Jingwen
黑色素瘤
基因治疗
发表日期：2026
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