日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural insights into the mechanism of protein transport by the Type 9 Secretion System translocon

型分泌系统转运蛋白的蛋白质运输机制结构洞察

Frédéric Lauber #, Justin C Deme #, Xiaolong Liu, Andreas Kjær, Helen L Miller, Felicity Alcock, Susan M Lea, Ben C Berks

Structural basis for antibiotic transport and inhibition in PepT2

PepT2 中抗生素运输和抑制的结构基础

Joanne L Parker #, Justin C Deme #, Simon M Lichtinger #, Gabriel Kuteyi, Philip C Biggin, Susan M Lea, Simon Newstead

Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM

利用低温电子显微镜捕获钴胺素核糖开关的异质构象

Jienyu Ding, Justin C Deme, Jason R Stagno, Ping Yu, Susan M Lea, Yun-Xing Wang

Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40

亨廷顿蛋白功能亚域的描述及其与 HAP40 的相互作用

Matthew G Alteen, Justin C Deme, Claudia P Alvarez, Peter Loppnau, Ashley Hutchinson, Alma Seitova, Renu Chandrasekaran, Eduardo Silva Ramos, Christopher Secker, Mona Alqazzaz, Erich E Wanker, Susan M Lea, Cheryl H Arrowsmith, Rachel J Harding

Structural Basis of Directional Switching by the Bacterial Flagellum

细菌鞭毛方向转换的结构基础

Steven Johnson, Justin C Deme, Emily J Furlong, Joseph J E Caesar, Fabienne F V Chevance, Kelly T Hughes, Susan M Lea

Molecular structure of the intact bacterial flagellar basal body

完整细菌鞭毛基体的分子结构

Steven Johnson #, Emily J Furlong #, Justin C Deme, Ashley L Nord, Joseph J E Caesar, Fabienne F V Chevance, Richard M Berry, Kelly T Hughes, Susan M Lea

Molecular basis for redox control by the human cystine/glutamate antiporter system xc

人类胱氨酸/谷氨酸反向转运系统控制氧化还原的分子基础 xc

Joanne L Parker #, Justin C Deme #, Dimitrios Kolokouris, Gabriel Kuteyi, Philip C Biggin, Susan M Lea, Simon Newstead

Mechanism of lipid droplet formation by the yeast Sei1/Ldb16 Seipin complex

酵母Sei1/Ldb16 Seipin复合物形成脂滴的机制

Yoel A Klug, Justin C Deme #, Robin A Corey #, Mike F Renne #, Phillip J Stansfeld, Susan M Lea, Pedro Carvalho

Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals

PepT2 的低温电子显微镜结构揭示了哺乳动物中质子偶联肽和前药转运的结构基础

Joanne L Parker, Justin C Deme, Zhiyi Wu, Gabriel Kuteyi, Jiandong Huo, Raymond J Owens, Philip C Biggin, Susan M Lea, Simon Newstead0

Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1

亨廷顿蛋白结构由 HAP40 调控,并与外显子 1 发生多聚谷氨酰胺扩增特异性相互作用

Rachel J Harding, Justin C Deme, Johannes F Hevler, Sem Tamara, Alexander Lemak, Jeffrey P Cantle, Magdalena M Szewczyk, Nola Begeja, Siobhan Goss, Xiaobing Zuo, Peter Loppnau, Alma Seitova, Ashley Hutchinson, Lixin Fan, Ray Truant, Matthieu Schapira, Jeffrey B Carroll, Albert J R Heck, Susan M Lea,