文献库，生知库 | 链接生命科学的每一步

日期影响因子

Resveratrol (3, 5, 4'-Trihydroxy-trans-Stilbene) Attenuates a Mouse Model of Multiple Sclerosis by Altering the miR-124/Sphingosine Kinase 1 Axis in Encephalitogenic T Cells in the Brain

白藜芦醇（3, 5, 4'-三羟基反式二苯乙烯）通过改变脑内脑炎性 T 细胞中的 miR-124/鞘氨醇激酶 1 轴减轻小鼠多发性硬化症模型

期刊:Journal of Neuroimmune Pharmacology

影响因子:5.2

doi:10.1007/s11481-019-09842-5

K Alexa Orr Gandy, Jiajia Zhang, Prakash Nagarkatti, Mitzi Nagarkatti

多发性硬化症

发表日期：2019

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The role of gut microbiota in shaping the relapse-remitting and chronic-progressive forms of multiple sclerosis in mouse models

肠道菌群在小鼠模型中多发性硬化症复发缓解型和慢性进展型中的作用

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-019-43356-7

Gandy, K Alexa Orr; Zhang, Jiajia; Nagarkatti, Prakash; Nagarkatti, Mitzi

多发性硬化症

发表日期：2019

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Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis

新型鞘氨醇激酶 1 抑制剂 LCL351 可降低小鼠 DSS 诱发结肠炎的免疫反应

期刊:Prostaglandins & Other Lipid Mediators

影响因子:2.5

doi:10.1016/j.prostaglandins.2017.03.006

Michael J Pulkoski-Gross, Joachim D Uys, K Alexa Orr-Gandy, Nicolas Coant, Agnieszka B Bialkowska, Zdzislaw M Szulc, Aiping Bai, Alicja Bielawska, Danyelle M Townsend, Yusuf A Hannun, Lina M Obeid, Ashley J Snider

发表日期：2017

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Sphingosine 1-phosphate induces filopodia formation through S1PR2 activation of ERM proteins

鞘氨醇 1-磷酸通过 S1PR2 激活 ERM 蛋白诱导丝状伪足形成

期刊:Biochemical Journal

影响因子:4.4

doi:10.1042/BJ20120213

K Alexa Orr Gandy, Daniel Canals, Mohamad Adada, Masayuki Wada, Patrick Roddy, Ashley J Snider, Yusuf A Hannun, Lina M Obeid

发表日期：2013

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Epidermal growth factor-induced cellular invasion requires sphingosine-1-phosphate/sphingosine-1-phosphate 2 receptor-mediated ezrin activation

表皮生长因子诱导的细胞侵袭需要鞘氨醇-1-磷酸/鞘氨醇-1-磷酸2受体介导的ezrin激活。

期刊:FASEB Journal

影响因子:4.2

doi:10.1096/fj.13-228460

Orr Gandy, K Alexa; Adada, Mohamad; Canals, Daniel; Carroll, Brittany; Roddy, Patrick; Hannun, Yusuf A; Obeid, Lina M

细胞生物学

发表日期：2013

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Sphingosine kinase 1 regulates tumor necrosis factor-mediated RANTES induction through p38 mitogen-activated protein kinase but independently of nuclear factor κB activation

鞘氨醇激酶 1 通过 p38 丝裂原活化蛋白激酶调节肿瘤坏死因子介导的 RANTES 诱导，但独立于核因子 κB 活化

期刊:Journal of Biological Chemistry

doi:10.1074/jbc.M113.489443

Mohamad M Adada, K Alexa Orr-Gandy, Ashley J Snider, Daniel Canals, Yusuf A Hannun, Lina M Obeid, Christopher J Clarke

发表日期：2013

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Targeting the sphingosine kinase/sphingosine 1-phosphate pathway in disease: review of sphingosine kinase inhibitors

靶向鞘氨醇激酶/鞘氨醇-1-磷酸通路治疗疾病：鞘氨醇激酶抑制剂综述

doi:10.1016/j.bbalip.2012.07.002

Orr Gandy, K Alexa; Obeid, Lina M

发表日期：2013

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Sphingosine kinase: Role in regulation of bioactive sphingolipid mediators in inflammation

鞘氨醇激酶：在炎症中调节生物活性鞘脂介质的作用

doi:10.1016/j.biochi.2010.02.008

Snider, Ashley J; Orr Gandy, K Alexa; Obeid, Lina M

发表日期：2010

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A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis

鞘氨醇激酶 1 在葡聚糖硫酸钠诱导的结肠炎中的作用

期刊:FASEB Journal

影响因子:4.2

doi:10.1096/fj.08-118109

Snider, Ashley J; Kawamori, Toshihiko; Bradshaw, Sarah G; Orr, K Alexa; Gilkeson, Gary S; Hannun, Yusuf A; Obeid, Lina M

发表日期：2009

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