日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Low-Molecular Weight Cyclin E Confers a Vulnerability to PKMYT1 Inhibition in Triple-Negative Breast Cancer.

低分子量细胞周期蛋白 E 使三阴性乳腺癌对 PKMYT1 抑制剂敏感

Li Mi, Lulla Amriti R, Wang Yan, Tsavaschidis Spyros, Wang Fuchenchu, Karakas Cansu, Nguyen Tuyen D T, Bui Tuyen N, Pina Marc A, Chen Mei-Kuang, Mastoraki Sofia, Multani Asha S, Fowlkes Natalie W, Sahin Aysegul, Marshall C Gary, Hunt Kelly K, Keyomarsi Khandan

Exploring Novel Frontiers: Leveraging STAT3 Signaling for Advanced Cancer Therapeutics

探索全新领域:利用 STAT3 信号通路进行癌症治疗

Adesoye, Taiwo; Tripathy, Debasish; Hunt, Kelly K; Keyomarsi, Khandan

Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time

针对视网膜母细胞瘤和DNA合成通路进行顺序靶向治疗是一种可实时监测的肉瘤治疗策略

Nguyen, Tuyen Duong Thanh; Wang, Yan; Bui, Tuyen N; Lazcano, Rossana; Ingram, Davis R; Yi, Min; Vakulabharanam, Varshini; Luo, Linjie; Pina, Marc A; Karakas, Cansu; Li, Mi; Kettner, Nicole M; Somaiah, Neeta; Hougton, Peter J; Mawlawi, Osama; Lazar, Alexander J; Hunt, Kelly K; Keyomarsi, Khandan

Low-molecular-weight cyclin E deregulates DNA replication and damage repair to promote genomic instability in breast cancer

低分子量细胞周期蛋白E通过扰乱DNA复制和损伤修复来促进乳腺癌基因组的不稳定性

Li, Mi; Tsavachidis, Spiridon; Wang, Fuchenchu; Bui, Tuyen; Nguyen, Tuyen Duong Thanh; Luo, Linjie; Multani, Asha S; Bondy, Melissa L; Hunt, Kelly K; Keyomarsi, Khandan

LMW cyclin E and its novel catalytic partner CDK5 are therapeutic targets and prognostic biomarkers in salivary gland cancers

低分子量细胞周期蛋白E及其新型催化伴侣CDK5是唾液腺癌的治疗靶点和预后生物标志物。

Lulla, Amriti R; Akli, Said; Karakas, Cansu; Ha, Min Jin; Fowlkes, Natalie W; Mitani, Yoshitsugu; Bui, Tuyen; Wang, Jing; Rao, Xiayu; Hunt, Kelly K; Meijer, Laurent; El-Naggar, Adel K; Keyomarsi, Khandan

Specific, reversible G1 arrest by UCN-01 in vivo provides cytostatic protection of normal cells against cytotoxic chemotherapy in breast cancer

UCN-01在体内特异性、可逆的G1期阻滞可为乳腺癌中的正常细胞提供细胞抑制保护,使其免受细胞毒性化疗的侵害。

Mull, Benjamin B; Livingston, J Andrew; Patel, Nalini; Bui, Tuyen; Hunt, Kelly K; Keyomarsi, Khandan

Low-Molecular-Weight Cyclin E in Human Cancer: Cellular Consequences and Opportunities for Targeted Therapies

人类癌症中的低分子量细胞周期蛋白E:细胞后果及靶向治疗的机会

Caruso, Joseph A; Duong, Mylinh T; Carey, Jason P W; Hunt, Kelly K; Keyomarsi, Khandan

PKCiota promotes ovarian tumor progression through deregulation of cyclin E

PKCiota 通过失调细胞周期蛋白 E 促进卵巢肿瘤进展

A Nanos-Webb, T Bui, C Karakas, D Zhang, J P W Carey, G B Mills, K K Hunt, K Keyomarsi

Cytoplasmic Cyclin E and Phospho-Cyclin-Dependent Kinase 2 Are Biomarkers of Aggressive Breast Cancer

细胞质细胞周期蛋白E和磷酸化细胞周期蛋白依赖性激酶2是侵袭性乳腺癌的生物标志物

Karakas, Cansu; Biernacka, Anna; Bui, Tuyen; Sahin, Aysegul A; Yi, Min; Akli, Said; Schafer, Jolie; Alexander, Angela; Adjapong, Opoku; Hunt, Kelly K; Keyomarsi, Khandan

Estrogen receptor alpha is cell cycle-regulated and regulates the cell cycle in a ligand-dependent fashion

雌激素受体α受细胞周期调控,并以配体依赖的方式调控细胞周期。

JavanMoghadam, Sonia; Weihua, Zhang; Hunt, Kelly K; Keyomarsi, Khandan