日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Foundational Shift in Models for Enzyme Function

酶功能模型的基础性转变

Klinman, Judith P; Miller, Susan M; Richards, Nigel G J

Dynamically Interacting Protein Networks Provide a Mechanism to Overcome the Enormous Intrinsic Barrier to Orotidine 5'-Monophosphate Decarboxylation

动态相互作用的蛋白质网络提供了一种克服乳清酸5'-单磷酸脱羧反应巨大内在障碍的机制

Dubey, Pankaj; Somani, Anish; Lin, Jessica; Iavarone, Anthony T; Klinman, Judith P

Identification of Scaffold Specific Energy Transfer Networks in the Enthalpic Activation of Orotidine 5'-Monophosphate Decarboxylase

鉴定乳清酸5'-单磷酸脱羧酶焓活化过程中的骨架特异性能量转移网络

Dubey, Pankaj; Somani, Anish; Lin, Jessica; Iavarone, Anthony T; Klinman, Judith P

Correlated Motion-Based Residue Network Analysis Reveals the Distal Thermal Activation in Soybean Lipoxygenase

基于相关运动的残基网络分析揭示大豆脂氧合酶的远端热激活

Jiang, Yaoyukun; Cordova, Jaden P; Klinman, Judith P

Sequelae and reversal of age-dependent alterations in mitochondrial dynamics via autophagy enhancement in reprogrammed human neurons

通过自噬增强重编程人类神经元中线粒体动力学随年龄变化的后果和逆转

Klinman, Eva; Kwon, Ji-Sun; Dolle, Roland E; Pak, Stephen C; Silverman, Gary A; Perlmutter, David H; Yoo, Andrew S

Temporal Resolution of Activity-Related Solvation Dynamics in the TIM Barrel Enzyme Murine Adenosine Deaminase

小鼠腺苷脱氨酶TIM桶状酶活性相关溶剂化动力学的时间分辨率

Gao, Shuaihua; Wu, Xin Ting; Zhang, Wenju; Richardson, Tyre; Barrow, Samuel L; Thompson-Kucera, Christian A; Iavarone, Anthony T; Klinman, Judith P

Hydrogen-Deuterium Exchange Mass Spectrometry Identifies Local and Long-Distance Interactions within the Multicomponent Radical SAM Enzyme, PqqE

氢氘交换质谱法鉴定多组分自由基SAM酶PqqE内部的局部和长程相互作用

Zhu, Wen; Iavarone, Anthony T; Klinman, Judith P

Replacement of Tyrosines by Unnatural Amino Acid Aminophenylalanine Leads to Metal-Mediated Aniline Free Radical Formation in a Copper Amine Oxidase

用非天然氨基酸氨基苯丙氨酸取代酪氨酸会导致铜胺氧化酶中金属介导的苯胺自由基生成。

Koehn, Eric M; Lang, Albert; Flores, Allison; Lambert, Claudia; Klinman, Judith

Novel SGCE Mutation in a Patient With Myoclonus-Dystonia: A Case Report

肌阵挛-肌张力障碍患者中发现新型SGCE基因突变:病例报告

Klinman, Eva; Gooch, Catherine; Perlmutter, Joel S; Davis, Albert A; Maiti, Baijayanta

Gene network landscape of mouse splenocytes reveals integrin complex as the A151 ODN-responsive hub molecule in the immune transcriptome

小鼠脾细胞基因网络图谱揭示整合素复合物是免疫转录组中对A151 ODN有反应的枢纽分子

Yazar, Volkan; Yilmaz, Ismail Cem; Bulbul, Artun; Klinman, Dennis M; Gursel, Ihsan