P02.18.A TUMOR-SECRETED (R)-2-HYDROXYGLUTARATE ACTIVATES NEURONS TO PRODUCE MITOGENS THAT PROMOTE IDH MUTANT GLIOMA GROWTH, FOSTERING A PARACRINE SIGNALING LOOP WITHIN THE TUMOR MICROENVIRONMENT
P02.18.A 肿瘤分泌的 (R)-2-羟基戊二酸激活神经元产生促有丝分裂原，促进 IDH 突变型胶质瘤的生长，从而在肿瘤微环境中形成旁分泌信号环路
期刊:Journal of the American Medical Association
影响因子:55
doi:10.1001/jama.2025.0584
Nerlekar, Nitesh; Vasanthakumar, Sheran A; Whitmore, Kristyn; Soh, Cheng Hwee; Chan, Jasmine; Goel, Vinay; Ryan, Jacqueline; Jones, Catherine; Stanton, Tony; Mitchell, Geoffrey; Tonkin, Andrew; Watts, Gerald F; Nicholls, Stephen J; Marwick, Thomas H; Birabaharan, Morgan; Kaelber, David C; Mehta, Sanjay R; Lee, C K; Nagashima, H; Cash, S; Miller, J J; Wakimoto, H; Cahill, D P
