Abundance-biased codon diversification prevents recombination in AAV production and ensures robust in vivo expression of functional FRET sensors.
丰度偏向密码子多样化可防止 AAV 生产中的重组,并确保功能性 FRET 传感器在体内稳定表达
期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-025-08677-6
Dernic Jan, Eleftheriou Afroditi, Vasilikos Lazaros, Rauch Melanie, Imseng Pascal, Zanker Henri S, Looser Zoe J, Meister Rachel M, Velasquez Moros Felipe, Kagan Tomer, Laviv Tal, Paterna Jean-Charles, Arand Michael, Saab Aiman S, Weber Bruno, Ravotto Luca