日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Plitidepsin in combination with dexamethasone (ADMYRE trial) versus an external control arm of pomalidomide plus dexamethasone in patients with relapsed/refractory multiple myeloma

在复发/难治性多发性骨髓瘤患者中，普利替地辛联合地塞米松（ADMYRE试验）与泊马度胺联合地塞米松的外部对照组进行比较

期刊:Annals of Hematology
影响因子:2.4
doi:10.1007/s00277-026-06811-w
Ludwig, Heinz; Terpos, Evangelos; Boccadoro, Mario; Martínez, Sara; Kahatt, Carmen; Jiménez, Javier; Nieto, Antonio; Extremera, Sonia; Gómez, Javier; Alfaro, Vicente; Davi, Ruthanna; Yin, Xiang; Mateos, María Victoria
多发性骨髓瘤
骨髓瘤
发表日期：2026
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Randomized Phase III Study (ADMYRE) of Plitidepsin in Combination with Dexamethasone vs. Dexamethasone Alone in Relapsed/Refractory Multiple Myeloma: Results for Patients Aged <75 Years

普利替地辛联合地塞米松与单用地塞米松治疗复发/难治性多发性骨髓瘤的随机III期研究（ADMYRE）：<75岁患者的结果

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers17213482
Mateos, María Victoria; Terpos, Evangelos; Martínez, Sara; Kahatt, Carmen; Jiménez, Javier; Extremera, Sonia; Gómez, Javier; Alfaro, Vicente; Ludwig, Heinz
多发性骨髓瘤
骨髓瘤
发表日期：2025
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Phase I results on the efficacy, safety and pharmacokinetics of lurbinectedin and irinotecan in advanced solid tumors

鲁比替丁和伊立替康治疗晚期实体瘤的疗效、安全性和药代动力学I期研究结果

期刊:Investigational New Drugs
影响因子:2.7
doi:10.1007/s10637-025-01583-y
Falcón, Alejandro; Ponce, Santiago; Cote, Gregory M; Gil, Ana; Lin, Jessica J; Bockorny, Bruno; Martínez, Julia; Kahatt, Carmen; Martinez, Sara; Zubiaur, Pablo; Siguero, Mariano; Cullell-Young, Martin; Jiménez, Javier; Zugazagoitia, Jon; Paz-Ares, Luis
发表日期：2025
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SaLudo: a randomized phase IIb/III study of lurbinectedin plus doxorubicin as first-line treatment in leiomyosarcoma

SaLudo：一项随机 IIb/III 期研究，评估 lurbinectedin 联合多柔比星作为平滑肌肉瘤一线治疗方案的疗效

期刊:Future Oncology
影响因子:2.6
doi:10.1080/14796694.2025.2463798
Cote, Gregory M; Chawla, Sant P; Demetri, George; Kasper, Bernd; Jones, Robin L; Broto, Javier Martin; Wooley, Joseph; Weiss, Mia C; Tafuto, Salvatore; Badalamenti, Giuseppe; Carrasco, Irene; Peinado, Paloma; Blay, Jean-Yves; Boggio, Gaston; Fernandez, Cristian; Nieto, Antonio; Kahatt, Carmen; Alfaro, Vicente; Le Cesne, Axel
发表日期：2025
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Pharmacokinetics and Safety of Lurbinectedin Administrated with Itraconazole in Cancer Patients: A Drug-Drug Interaction Study

鲁比奈德定与伊曲康唑联合用药在癌症患者中的药代动力学和安全性：一项药物相互作用研究

期刊:Marine Drugs
影响因子:5.4
doi:10.3390/md22040178
Moreno, Irene; Hernández, Tatiana; Calvo, Emiliano; Fudio, Salvador; Kahatt, Carmen; Martínez, Sara; Iglesias, Jorge Luis; Calafati, Román Octavio; Pérez-Ramos, Laura; Montilla, Lola; Zeaiter, Ali; Lubomirov, Rubin
肿瘤
肿瘤免疫
发表日期：2024
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A phase I safety and efficacy clinical trial of plocabulin and gemcitabine in patients with advanced solid tumors

普洛卡布林联合吉西他滨治疗晚期实体瘤患者的I期安全性和有效性临床试验

期刊:Investigational New Drugs
影响因子:2.7
doi:10.1007/s10637-024-01458-8
Ghalib, Mohammad H; Pulla, Mariano Provencio; De Miguel Luken, Maria J; de Juan, Virginia Calvo; Chaudhary, Imran; Hammami, M Bakri; Vikash, Sindhu; Maitra, Radhashree; Martinez, Sara; Kahatt, Carmen; Extremera, Sonia; Fudio, Salvador; Goel, Sanjay
发表日期：2024
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Phase I study of plitidepsin in combination with bortezomib and dexamethasone in patients with relapsed/refractory multiple myeloma

普利替地辛联合硼替佐米和地塞米松治疗复发/难治性多发性骨髓瘤患者的I期研究

期刊:Cancer Medicine
影响因子:3.1
doi:10.1002/cam4.5250
Mateos, María Victoria; Prosper, Felipe; Martin Sánchez, Jesús; Ocio, Enrique M; Oriol, Albert; Motlló, Cristina; Michot, Jean-Marie; Jarque, Isidro; Iglesias, Rebeca; Solé, María; Martínez, Sara; Kahatt, Carmen; Fudio, Salvador; Corral, Gema; Zeaiter, Ali; Montilla, Lola; Ribrag, Vincent
多发性骨髓瘤
骨髓瘤
发表日期：2023
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Lurbinectedin in patients with pretreated endometrial cancer: results from a phase 2 basket clinical trial and exploratory translational study

Lurbinectedin治疗既往接受过治疗的子宫内膜癌患者：一项II期篮式临床试验和探索性转化研究的结果

期刊:Investigational New Drugs
影响因子:2.7
doi:10.1007/s10637-023-01383-2
Kristeleit, Rebecca; Leary, Alexandra; Delord, Jean Pierre; Moreno, Victor; Oaknin, Ana; Castellano, Daniel; Shappiro, Geoffrey I; Fernández, Cristian; Kahatt, Carmen; Alfaro, Vicente; Siguero, Mariano; Rueda, Daniel; Zeaiter, Ali; Awada, Ahmad; Santaballa, Ana; Zaman, Khalil; Sehouli, Jalid; Subbiah, Vivek
肿瘤
子宫内膜癌
肿瘤免疫
发表日期：2023
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Antitumor Activity of Lurbinectedin, a Selective Inhibitor of Oncogene Transcription, in Patients with Relapsed Ewing Sarcoma: Results of a Basket Phase II Study

选择性癌基因转录抑制剂鲁比奈克汀在复发性尤文氏肉瘤患者中的抗肿瘤活性：一项篮式 II 期研究的结果

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-22-0696
Subbiah, Vivek; Braña, Irene; Longhi, Alessandra; Boni, Valentina; Delord, Jean-Pierre; Awada, Ahmad; Boudou-Rouquette, Pascaline; Sarantopoulos, John; Shapiro, Geoffrey I; Elias, Anthony; Ratan, Ravin; Fernandez, Cristian; Kahatt, Carmen; Cullell-Young, Martin; Siguero, Mariano; Zeaiter, Ali; Chawla, Sant P
肿瘤
肿瘤免疫
发表日期：2022
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Lurbinectedin, a selective inhibitor of oncogenic transcription, in patients with pretreated germline BRCA1/2 metastatic breast cancer: results from a phase II basket study

鲁比奈克汀（一种选择性致癌转录抑制剂）用于治疗既往接受过治疗的生殖系 BRCA1/2 转移性乳腺癌患者：一项 II 期篮式研究的结果

期刊:ESMO Open
影响因子:8.3
doi:10.1016/j.esmoop.2022.100571
Boni, V; Pistilli, B; Braña, I; Shapiro, G I; Trigo, J; Moreno, V; Castellano, D; Fernández, C; Kahatt, C; Alfaro, V; Siguero, M; Zeaiter, A; Longo, F; Zaman, K; Antón, A; Paredes, A; Huidobro, G; Subbiah, V
BRCA1
肿瘤
肿瘤免疫
乳腺癌
发表日期：2022
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