日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Bumped Kinase Inhibitor BKI-1708 Interferes in Cytokinesis and Drives Baryzoite Conversion in the Cyst-Forming Apicomplexan Parasites Toxoplasma gondii, Neospora caninum and Besnoitia besnoiti

激酶抑制剂 BKI-1708 干扰胞质分裂并驱动包囊形成顶复门寄生虫弓形虫、犬新孢子虫和贝氏贝氏虫的重殖子转化

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms27062914
de Sousa, Maria Cristina Ferreira; Müller, Joachim; Hänggeli, Kai Pascal Alexander; Heller, Manfred; Uldry, Anne-Christine; Braga-Lagache, Sophie; Leitao, Alexandre; Ortega-Mora, Luis-Miguel; Ojo, Kayode K; Van Voorhis, Wesley C; Hemphill, Andrew
信号转导
微生物学
发表日期：2026
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Potential Molecular Targets of the Broad-Range Antimicrobial Peptide Tyrothricin in the Apicomplexan Parasite Toxoplasma gondii

弓形虫（Toxoplasma gondii）中广谱抗菌肽酪菌素的潜在分子靶点

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines14010172
Amdouni, Yosra; Boubaker, Ghalia; Müller, Joachim; Sousa, Maria Cristina Ferreira de; Hänggeli, Kai Pascal Alexander; Uldry, Anne-Christine; Braga-Lagache, Sophie; Heller, Manfred; Hemphill, Andrew
发表日期：2026
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Pleiotropic Effects on Tachyzoite and Host Cell Proteomes in Knock-Out Clones of the Open Reading Frames 297720 and 319730 Constitutively Expressed in T. gondii ShSp1 Tachyzoites

在弓形虫ShSp1速殖子中组成型表达的开放阅读框297720和319730敲除克隆中，速殖子和宿主细胞蛋白质组存在多效性效应

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms262110433
Hänggeli, Kai Pascal Alexander; Müller, Joachim; Heller, Manfred; Uldry, Anne-Christine; Braga-Lagache, Sophie; Arranz-Solís, David; Ortega-Mora, Luis-Miguel; Hemphill, Andrew
细胞生物学
发表日期：2025
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In Vivo Safety and Efficacy of Thiosemicarbazones in Experimental Mice Infected with Toxoplasma gondii Oocysts.

硫代氨基脲类药物在感染弓形虫卵囊的实验小鼠体内的安全性和有效性

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines13081879
Semeraro Manuela, Boubaker Ghalia, Scaccaglia Mirco, Imhof Dennis, de Sousa Maria Cristina Ferreira, Hänggeli Kai Pascal Alexander, Löwe Anitha, Genchi Marco, Kramer Laura Helen, Vismarra Alice, Pelosi Giorgio, Bisceglie Franco, Ortega-Mora Luis Miguel, Müller Joachim, Hemphill Andrew
炎症/感染
发表日期：2025
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TaqMan-quantitative PCR assays applied in Neospora caninum knock-outs generated through CRISPR-Cas9 allow to determine the copy numbers of integrated dihydrofolate reductase-thymidylate synthase drug selectable markers

利用 CRISPR-Cas9 技术在犬新孢子虫基因敲除株中应用 TaqMan 定量 PCR 检测，可以确定整合的二氢叶酸还原酶-胸苷酸合成酶药物选择标记的拷贝数。

期刊:Frontiers in Cellular and Infection Microbiology
影响因子:4.8
doi:10.3389/fcimb.2024.1419209
Rico-San Román, Laura; Hänggeli, Kai Pascal Alexander; Hemphill, Andrew; Horcajo, Pilar; Collantes-Fernández, Esther; Ortega-Mora, Luis Miguel; Boubaker, Ghalia
发表日期：2024
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Efficacy of the bumped kinase inhibitor BKI-1708 against the cyst-forming apicomplexan parasites Toxoplasma gondii and Neospora caninum in vitro and in experimentally infected mice

体外和实验感染小鼠体内，凸起激酶抑制剂BKI-1708对形成包囊的顶复门寄生虫弓形虫和犬新孢子虫的疗效

期刊:International Journal for Parasitology-Drugs and Drug Resistance
影响因子:3.4
doi:10.1016/j.ijpddr.2024.100553
de Sousa, Maria Cristina Ferreira; Imhof, Dennis; Hänggeli, Kai Pascal Alexander; Choi, Ryan; Hulverson, Matthew A; Arnold, Samuel L M; Van Voorhis, Wesley C; Fan, Erkang; Roberto, Sánchez-Sánchez; Ortega-Mora, Luis M; Hemphill, Andrew
炎症/感染
信号转导
微生物学
发表日期：2024
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In vitro and in vivo activities of a trithiolato-diRuthenium complex conjugated with sulfadoxine against the apicomplexan parasite Toxoplasma gondii

三硫醇二钌配合物与磺胺多辛偶联物对弓形虫（Toxoplasma gondii）的体外和体内活性

期刊:International Journal for Parasitology-Drugs and Drug Resistance
影响因子:3.4
doi:10.1016/j.ijpddr.2024.100544
Boubaker, Ghalia; Bernal, Alice; Vigneswaran, Anitha; Imhof, Dennis; de Sousa, Maria Cristina Ferreira; Hänggeli, Kai Pascal Alexander; Haudenschild, Noé; Furrer, Julien; Păunescu, Emilia; Desiatkina, Oksana; Hemphill, Andrew
发表日期：2024
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Comparative Proteomic Analysis of Toxoplasma gondii RH Wild-Type and Four SRS29B (SAG1) Knock-Out Clones Reveals Significant Differences between Individual Strains

对弓形虫RH野生型和四个SRS29B（SAG1）敲除克隆株的比较蛋白质组学分析揭示了不同毒株之间的显著差异

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms241310454
Hänggeli, Kai Pascal Alexander; Hemphill, Andrew; Müller, Norbert; Heller, Manfred; Uldry, Anne-Christine; Braga-Lagache, Sophie; Müller, Joachim; Boubaker, Ghalia
RS2
发表日期：2023
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Immunization with a Multivalent Listeria monocytogenes Vaccine Leads to a Strong Reduction in Vertical Transmission and Cerebral Parasite Burden in Pregnant and Non-Pregnant Mice Infected with Neospora caninum

用多价单核细胞增生李斯特菌疫苗进行免疫接种可显著降低感染犬新孢子虫的妊娠和非妊娠小鼠的垂直传播率和脑寄生虫负荷。

期刊:Vaccines
影响因子:3.4
doi:10.3390/vaccines11010156
Imhof, Dennis; Pownall, William; Hänggeli, Kai Pascal Alexander; Monney, Camille; Román, Laura Rico-San; Ortega-Mora, Luis-Miguel; Forterre, Franck; Oevermann, Anna; Hemphill, Andrew
炎症/感染
神经科学
微生物学
单核细胞
细胞生物学
免疫/内分泌
发表日期：2023
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In Vitro versus in Mice: Efficacy and Safety of Decoquinate and Quinoline-O-Carbamate Derivatives against Experimental Infection with Neospora caninum Tachyzoites.

体外与小鼠体内：十喹啉和喹啉-O-氨基甲酸酯衍生物对犬新孢子虫速殖子实验感染的疗效和安全性

期刊:Pathogens
影响因子:3.3
doi:10.3390/pathogens12030447
Ramseier Jessica, Imhof Dennis, Hänggeli Kai Pascal Alexander, Anghel Nicoleta, Boubaker Ghalia, Beteck Richard M, Ortega-Mora Luis-Miguel, Haynes Richard K, Hemphill Andrew
炎症/感染
发表日期：2023
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