Antitrypanosomal quinazolines targeting lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease
靶向赖氨酰tRNA合成酶的抗锥虫喹唑啉类药物在急性恰加斯病小鼠模型中显示出部分疗效。
期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.adu4564
Tulloch, Lindsay B; Tawell, Hugh; Taylor, Annie E; Lima, Marta Lopes; Dawson, Alice; Carvalho, Sandra; Wall, Richard J; Corpas-Lopez, Victoriano; Dey, Gourav; Duggan, Jack; Magalhaes, Luma Godoy; Torrie, Leah S; Frame, Laura; Robinson, David; Patterson, Stephen; Tinti, Michele; Weaver, George W; Robinson, William J; Cal, Monica; Kaiser, Marcel; Mäser, Pascal; Sjö, Peter; Perry, Benjamin; Kelly, John M; Francisco, Amanda Fortes; Bhambra, Avninder S; Wyllie, Susan
