日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Targeting Recipient Dendritic Cells with Sialic Acid-Modified Donor Alloantigen Prolongs Skin Transplant Survival

利用唾液酸修饰的供体同种异体抗原靶向受体树突状细胞可延长皮肤移植存活期

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26136168
Sen, Monica; Peng, Qi; Ratnasothy, Kulachelvy; Ambrosini, Martino; Kalay, Hakan; Bazoer, Jordan; Adams, Kate E; Ouazzani, Nouhad El; Ababou, Abdessamad; Guiliano, David B; Saldaña, Jose I; Kooyk, Yvette van; Lombardi, Giovanna; Smyth, Lesley A
树突状细胞
信号转导
细胞生物学
树突状细胞
免疫/内分泌
发表日期：2025
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Rational design of FVIII sialylated peptides to target Siglec-3 and Siglec-9 and improve peptide formulations for reverse vaccines.

合理设计 FVIII 唾液酸化肽以靶向 Siglec-3 和 Siglec-9，并改进反向疫苗的肽制剂

期刊:Frontiers in Bioengineering and Biotechnology
影响因子:4.8
doi:10.3389/fbioe.2025.1558627
Nardini Eleonora, Keumatio Doungstop Brigitte-Carole, Gerpe-Amor Tania, de Haas Aram M, de Kok Mike, Peterse Evert, Kalay Hakan, Li Rui-Jún E, Chiodo Fabrizio, Silipo Alba, Voorberg Jan, van Kooyk Yvette
发表日期：2025
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α2-3 Sialic Acids-Decorated Allergens Exert a Tolerogenic Effect on CD4+ T Cells from Der p 2-Allergic Patients

α2-3唾液酸修饰的过敏原对Der p 2过敏患者的CD4+ T细胞具有耐受性作用

期刊:International Archives of Allergy and Immunology
影响因子:1.8
doi:10.1159/000543157
Keumatio Doungtsop, Brigitte-Carole; Nardini, Eleonora; Peterse, Evert E; Kalay, Hakan; Versteeg, Serge A; van Ree, Ronald; de Jong, Esther E C; van Kooyk, Yvette
T细胞
T细胞
细胞生物学
CD4
免疫/内分泌
发表日期：2025
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Vaccination with DC-SIGN-Targeting αGC Liposomes Leads to Tumor Control, Irrespective of Suboptimally Activated T-Cells

即使T细胞活化程度不足，使用靶向DC-SIGN的αGC脂质体进行疫苗接种也能控制肿瘤。

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics16050581
de Haas, Aram M; Stolk, Dorian A; Schetters, Sjoerd T T; Goossens-Kruijssen, Laura; Keuning, Eelco; Ambrosini, Martino; Boon, Louis; Kalay, Hakan; Storm, Gert; van der Vliet, Hans J; de Gruijl, Tanja D; van Kooyk, Yvette
肿瘤
T细胞
肿瘤免疫
T细胞
细胞生物学
免疫/内分泌
发表日期：2024
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Development of a Versatile Cancer Vaccine Format Targeting Antigen-Presenting Cells Using Proximity-Based Sortase A-Mediated Ligation of T-Cell Epitopes

利用基于邻近性的A型分选酶介导的T细胞表位连接，开发一种靶向抗原呈递细胞的多功能癌症疫苗形式

期刊:Bioconjugate Chemistry
影响因子:3.9
doi:10.1021/acs.bioconjchem.4c00403
Wang, Aru Z; Brink, Hendrik J; Bouma, Rianne G; Affandi, Alsya J; Nijen Twilhaar, Maarten K; Heijnen, Dijmphna A M; van Elk, Joelle; Maaskant, Janneke J; Konijn, Veronique A L; Stolwijk, Joeke G C; Kalay, Hakan; Olesek, Katarina; van Kooyk, Yvette; van der Schoot, Johan M S; Bentlage, Arthur E H; Scheeren, Ferenc A; Verdoes, Martijn; Vidarsson, Gestur; Kuijl, Coenraad P; den Haan, Joke M M
肿瘤
T细胞
肿瘤免疫
T细胞
细胞生物学
免疫/内分泌
发表日期：2024
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Incorporation of Toll-Like Receptor Ligands and Inflammasome Stimuli in GM3 Liposomes to Induce Dendritic Cell Maturation and T Cell Responses

将 Toll 样受体配体和炎症小体刺激物整合到 GM3 脂质体中以诱导树突状细胞成熟和 T 细胞反应

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2022.842241
Nijen Twilhaar, Maarten K; Czentner, Lucas; Bouma, Rianne G; Olesek, Katarzyna; Grabowska, Joanna; Wang, Aru Zeling; Affandi, Alsya J; Belt, Saskia C; Kalay, Hakan; van Nostrum, Cornelus F; van Kooyk, Yvette; Storm, Gert; den Haan, Joke M M
炎症
T细胞
炎症/感染
信号转导
树突状细胞
Toll-Like Receptor
细胞生物学
炎性小体
树突状细胞
免疫/内分泌
发表日期：2022
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CD169 Defines Activated CD14(+) Monocytes With Enhanced CD8(+) T Cell Activation Capacity

CD169 可识别具有增强的 CD8(+) T 细胞活化能力的活化 CD14(+) 单核细胞。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2021.697840
Affandi, Alsya J; Olesek, Katarzyna; Grabowska, Joanna; Nijen Twilhaar, Maarten K; Rodríguez, Ernesto; Saris, Anno; Zwart, Eline S; Nossent, Esther J; Kalay, Hakan; de Kok, Michael; Kazemier, Geert; Stöckl, Johannes; van den Eertwegh, Alfons J M; de Gruijl, Tanja D; Garcia-Vallejo, Juan J; Storm, Gert; van Kooyk, Yvette; den Haan, Joke M M
CD16
CD14
T细胞
CD8
单核细胞
细胞生物学
发表日期：2021
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Palmitoylated antigens for the induction of anti-tumor CD8(+) T cells and enhanced tumor recognition

棕榈酰化抗原可诱导抗肿瘤CD8(+) T细胞并增强肿瘤识别

期刊:Molecular Therapy-Oncolytics
影响因子:5.3
doi:10.1016/j.omto.2021.04.009
Stolk, Dorian A; Horrevorts, Sophie K; Schetters, Sjoerd T T; Kruijssen, Laura J W; Duinkerken, Sanne; Keuning, Eelco; Ambrosini, Martino; Kalay, Hakan; van de Ven, Rieneke; Garcia-Vallejo, Juan J; de Gruijl, Tanja D; van Vliet, Sandra J; van Kooyk, Yvette
肿瘤
T细胞
肿瘤免疫
CD8
T细胞
细胞生物学
免疫/内分泌
发表日期：2021
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Comparison of Protein and Peptide Targeting for the Development of a CD169-Based Vaccination Strategy Against Melanoma

蛋白质靶向和肽靶向在基于CD169的黑色素瘤疫苗策略开发中的比较

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2018.01997
van Dinther, Dieke; Veninga, Henrike; Revet, Mirjam; Hoogterp, Leoni; Olesek, Katarzyna; Grabowska, Joanna; Borg, Ellen G F; Kalay, Hakan; van Kooyk, Yvette; den Haan, Joke M M
CD16
黑色素瘤
发表日期：2018
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Targeting Mycobacterium tuberculosis Antigens to Dendritic Cells via the DC-Specific-ICAM3-Grabbing-Nonintegrin Receptor Induces Strong T-Helper 1 Immune Responses

通过树突状细胞特异性ICAM3结合非整合素受体将结核分枝杆菌抗原靶向树突状细胞，可诱导强烈的T辅助细胞1型免疫反应。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2018.00471
Velasquez, Lis Noelia; Stüve, Philipp; Gentilini, Maria Virginia; Swallow, Maxine; Bartel, Judith; Lycke, Nils Yngve; Barkan, Daniel; Martina, Mariana; Lujan, Hugo D; Kalay, Hakan; van Kooyk, Yvette; Sparwasser, Tim D; Berod, Luciana
树突状细胞
信号转导
细胞生物学
树突状细胞
免疫/内分泌
发表日期：2018
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