日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reduction of RAD23A extends lifespan and mitigates pathology in a mouse model of TDP-43 proteinopathy.

RAD23A 的减少可延长 TDP-43 蛋白病小鼠模型的寿命并减轻病理。

Guo Xueshui, Prajapati Ravindra Singh, Chun Jiyeon, Byun Insuk, Gebis Kamil K, Wang Yi-Zhi, Ling Karen, Dalton Casey, Blair Jeff A, Hamidianjahromi Anahid, Bachmann Gemma, Rigo Frank, Jafar-Nejad Paymaan, Savas Jeffrey N, Lee Min Jae, Sreedharan Jemeen, Kalb Robert G

In Vivo Screen of Parkinson's Disease GWAS Risk Genes Identifies ARIH2 as a Novel Regulator of α-Synuclein Toxicity in Dopaminergic Neurons

帕金森病全基因组关联研究风险基因的体内筛选发现ARIH2是多巴胺能神经元中α-突触核蛋白毒性的新型调节因子

Armakola, Maria; Wilen, Anika P; Bustos, Bernabe I; Song, Pingping; Wang, Yi-Zhi; Thomas, Adeyemi K; Belur, Nandkishore R; Mazzulli, Joseph R; Savas, Jeffrey N; Kalb, Robert G; Krainc, Dimitri

Ubiquitin Proteasome System Components, RAD23A and USP13, Modulate TDP-43 Solubility and Neuronal Toxicity.

泛素蛋白酶体系统成分 RAD23A 和 USP13 调节 TDP-43 溶解度和神经元毒性。

Dalton Casey, Mojsilovic-Petrovic Jelena, Safren Nathaniel, Snoznik Carley, Gebis Kamil K, Wang Yi-Zhi, Sutter Alexandra B, Lamitina Todd, Savas Jeffrey N, Kalb Robert G

The molecular mechanism of uptake and cell-to-cell transmission of arginine-containing dipeptide repeat proteins.

含精氨酸二肽重复蛋白的摄取和细胞间传递的分子机制。

Sutter Alexandra B, Buksh Benito F, Mojsilovic-Petrovic Jelena, Dalton Casey, Till Nicholas A, Morgan Danielle C, MacMillan David W C, Kalb Robert G

Preconditioning of Caenorhabditis elegans to anoxic insult by inactivation of cholinergic, GABAergic and muscle activity

通过抑制胆碱能、GABA能和肌肉活动,使秀丽隐杆线虫预先适应缺氧损伤。

Bennett, Heather L; McClanahan, Patrick D; Fang-Yen, Christopher; Kalb, Robert G

HGG-02. NEUROPHYSIOLOGICAL SMALL MOLECULE SCREEN TO TARGET NEURON-GLIOMA INTERACTIONS IN PEDIATRIC HIGH-GRADE GLIOMAS

HGG-02. 针对儿童高级别胶质瘤中神经元-胶质瘤相互作用的神经生理小分子筛选

Tam, Sharon B; Waldeck, Nathan J; Wright, Matthew; Mojsilovic-Petrovic, Jelena; Baker, Erin M; Kiskinis, Evangelos; Bass, Joseph; Kalb, Robert G; Rogawski, David; Mulinyawe, Sara; Thomas, Craig; Monje, Michelle

A Critical Role for the GluA1 Accessory Protein, SAP97, in Cocaine Seeking

GluA1辅助蛋白SAP97在可卡因渴求中的关键作用

White, Samantha L; Ortinski, Pavel I; Friedman, Shayna H; Zhang, Lei; Neve, Rachael L; Kalb, Robert G; Schmidt, Heath D; Pierce, R Christopher

Genetically altering organismal metabolism by leptin-deficiency benefits a mouse model of amyotrophic lateral sclerosis

通过瘦素缺乏症对机体代谢进行基因改造,可使肌萎缩侧索硬化症小鼠模型获益

Lim, Maria A; Bence, Kendra K; Sandesara, Ishani; Andreux, Pénélope; Auwerx, Johan; Ishibashi, Jeff; Seale, Patrick; Kalb, Robert G

Oxygen sensing neurons and neuropeptides regulate survival after anoxia in developing C. elegans

氧感应神经元和神经肽调节发育中的秀丽隐杆线虫在缺氧后的存活

Flibotte, John J; Jablonski, Angela M; Kalb, Robert G

GluA1 promotes the activity-dependent development of motor circuitry in the developing segmental spinal cord

GluA1促进发育中节段性脊髓运动回路的活动依赖性发育。

Jablonski, Angela M; Kalb, Robert G