日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Manipulation of Redox Metabolism Using Pharmacologic Ascorbate Opens a Therapeutic Window for Radio-Sensitization by ATM Inhibitors in Colorectal Cancer.

利用药理学抗坏血酸操纵氧化还原代谢,为 ATM 抑制剂在结直肠癌中的放射增敏作用开辟治疗窗口

Callaghan Cameron M, Abukhiran Ibrahim M, Masaadeh Amr, Van Rheeden Richard V, Kalen Amanda L, Rodman Samuel N 3rd, Petronek Michael S, Mapuskar Kranti A, George Benjamin N, Coleman Mitchell C, Goswami Prabhat C, Allen Bryan G, Spitz Douglas R, Caster Joseph M

Utilization of Pharmacological Ascorbate to Enhance Hydrogen Peroxide-Mediated Radiosensitivity in Cancer Therapy.

利用药理学抗坏血酸增强过氧化氢介导的癌症治疗放射敏感性

Mehdi Zain, Petronek Michael S, Stolwijk Jeffrey M, Mapuskar Kranti A, Kalen Amanda L, Buettner Garry R, Cullen Joseph J, Spitz Douglas R, Buatti John M, Allen Bryan G

Assessment of Gadobutrol Safety in Combination with Ionizing Radiation Using a Preclinical MRI-Guided Radiotherapy Model

利用临床前MRI引导放射治疗模型评估钆布醇联合电离辐射的安全性

Petronek, Michael S; Steinbach, Emily J; Kalen, Amanda L; Builta, Zachariah J; Callaghan, Cameron M; Hyer, Dan E; Spitz, Douglas R; Flynn, Ryan T; Buatti, John M; Magnotta, Vincent A; Zepeda-Orozco, Diana; St-Aubin, Joël J; Allen, Bryan G

Combination Therapy with Radiation and PARP Inhibition Enhances Responsiveness to Anti-PD-1 Therapy in Colorectal Tumor Models.

放射治疗与 PARP 抑制剂联合治疗可增强结直肠肿瘤模型对 PD-1 抑制剂治疗的反应性

Seyedin Steven N, Hasibuzzaman M M, Pham Vivan, Petronek Michael S, Callaghan Cameron, Kalen Amanda L, Mapuskar Kranti A, Mott Sarah L, Spitz Douglas R, Allen Bryan G, Caster Joseph M

Arachidonate 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid contribute to stromal aging-induced progression of pancreatic cancer

花生四烯酸12-脂氧合酶和12-羟基二十碳四烯酸促进基质老化诱导的胰腺癌进展

Sarsour, Ehab H; Son, Jyung Mean; Kalen, Amanda L; Xiao, Wusheng; Du, Juan; Alexander, Matthew S; O'Leary, Brianne R; Cullen, Joseph J; Goswami, Prabhat C

Mitofusin 1 and optic atrophy 1 shift metabolism to mitochondrial respiration during aging

线粒体融合蛋白1和视神经萎缩蛋白1在衰老过程中将代谢转向线粒体呼吸。

Son, Jyung Mean; Sarsour, Ehab H; Kakkerla Balaraju, Anurag; Fussell, Jenna; Kalen, Amanda L; Wagner, Brett A; Buettner, Garry R; Goswami, Prabhat C

MnSOD and Cyclin B1 Coordinate a Mito-Checkpoint during Cell Cycle Response to Oxidative Stress

MnSOD 和细胞周期蛋白 B1 在细胞周期应对氧化应激的过程中协调线粒体检查点

Kalen, Amanda L; Ahmad, Iman M; Abdalla, Maher Y; O'Malley, Yunxia Q; Goswami, Prabhat C; Sarsour, Ehab H

Forkhead box M1 regulates quiescence-associated radioresistance of human head and neck squamous carcinoma cells

叉头盒M1调控人头颈部鳞状细胞癌细胞的静止期相关放射抗性

Eckers, Jaimee C; Kalen, Amanda L; Sarsour, Ehab H; Tompkins, Van S; Janz, Siegfried; Son, Jyung Mean; Doskey, Claire M; Buettner, Garry R; Goswami, Prabhat C

Selenoprotein P regulates 1-(4-Chlorophenyl)-benzo-2,5-quinone-induced oxidative stress and toxicity in human keratinocytes

硒蛋白P调节1-(4-氯苯基)-苯并-2,5-醌诱导的人类角质形成细胞氧化应激和毒性

Xiao, Wusheng; Zhu, Yueming; Sarsour, Ehab H; Kalen, Amanda L; Aykin-Burns, Nukhet; Spitz, Douglas R; Goswami, Prabhat C

Selenoprotein P inhibits radiation-induced late reactive oxygen species accumulation and normal cell injury

硒蛋白P抑制辐射诱导的晚期活性氧积累和正常细胞损伤

Eckers, Jaimee C; Kalen, Amanda L; Xiao, Wusheng; Sarsour, Ehab H; Goswami, Prabhat C