日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging

点击化学衍生的肟库揭示了神经毒剂抑制的丁酰胆碱酯酶的高效复活剂,适用于拟催化生物清除。

Čadež, Tena; Maček Hrvat, Nikolina; Šinko, Goran; Kalisiak, Jarosław; Radić, Zoran; Fokin, Valery V; Sharpless, Karl Barry; Taylor, Palmer; Kovarik, Zrinka

Targeting CD73 with AB680 (Quemliclustat), a Novel and Potent Small-Molecule CD73 Inhibitor, Restores Immune Functionality and Facilitates Antitumor Immunity

AB680(Quemliclustat)是一种新型强效小分子 CD73 抑制剂,可靶向 CD73,恢复免疫功能并促进抗肿瘤免疫

Dana Piovesan, Joanne B L Tan, Annette Becker, Jesus Banuelos, Nell Narasappa, Daniel DiRenzo, Kristen Zhang, Ada Chen, Elaine Ginn, Akshata R Udyavar, Fangfang Yin, Susan L Paprcka, Bhamini Purandare, Timothy W Park, Nikki Kimura, Jaroslaw Kalisiak, Stephen W Young, Jay P Powers, Uli Schindler, Kel

What Are the Needs of City Dwellers in Terms of the Development of Public Spaces? A Case Study of Participatory Budgeting in Częstochowa, Poland

城市居民在公共空间发展方面有哪些需求?以波兰琴斯托霍瓦市的参与式预算为例

Kołat, Katarzyna; Furmankiewicz, Marek; Kalisiak-Mędelska, Magdalena

Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases

评价通过抗三唑连接的高亲和力苯基四氢异喹啉醛肟作为磷酸化胆碱酯酶活化剂的活性

Maček Hrvat, Nikolina; Kalisiak, Jarosław; Šinko, Goran; Radić, Zoran; Sharpless, K Barry; Taylor, Palmer; Kovarik, Zrinka

Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis

点击化学促进抗菌 5-硝基咪唑加合蛋白质的全面鉴定,以发现治疗贾第虫病的替代药物靶点

Tineke Lauwaet, Yukiko Miyamoto, Sozaburo Ihara, Christine Le, Jarosław Kalisiak, Keith A Korthals, Majid Ghassemian, Diane K Smith, K Barry Sharpless, Valery V Fokin, Lars Eckmann

Neuroimaging results, short-term assessment of psychomotor development and the risk of autism spectrum disorder in extremely premature infants (≤28 GA) - a prospective cohort study (preliminary report)

极早产儿(≤28 GA)神经影像学结果、短期心理运动发育评估及自闭症谱系障碍风险——一项前瞻性队列研究(初步报告)

Rutkowska, Magdalena; Bekiesińska-Figatowska, Monika; Kmita, Grażyna; Terczyńska, Iwona; Polak, Katarzyna; Kalisiak, Marcin; Prażmowska, Dorota; Kiepura, Eliza; Szkudlińska-Pawlak, Sylwia; Seroczyńska, Małgorzata; Helwich, Ewa

A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans

HBS1L 的短剪接异构体连接人类细胞质外泌体和 SKI 复合物

Katarzyna Kalisiak, Tomasz M Kuliński, Rafał Tomecki, Dominik Cysewski, Zbigniew Pietras, Aleksander Chlebowski, Katarzyna Kowalska, Andrzej Dziembowski

Click Chemistry-Facilitated Structural Diversification of Nitrothiazoles, Nitrofurans, and Nitropyrroles Enhances Antimicrobial Activity against Giardia lamblia

点击化学促进的硝基噻唑、硝基呋喃和硝基吡咯的结构多样化增强了其对蓝氏贾第鞭毛虫的抗菌活性。

Kim, Wan Jung; Korthals, Keith A; Li, Suhua; Le, Christine; Kalisiak, Jarosław; Sharpless, K Barry; Fokin, Valery V; Miyamoto, Yukiko; Eckmann, Lars

Acylcarnitines are anticoagulants that inhibit factor Xa and are reduced in venous thrombosis, based on metabolomics data

根据代谢组学数据,酰基肉碱是一种抑制 Xa 因子的抗凝剂,在静脉血栓形成中可降低

Hiroshi Deguchi, Yajnavalka Banerjee, Sunia Trauger, Gary Siuzdak, Ewa Kalisiak, José A Fernández, Linh Hoang, Minerva Tran, Subramanian Yegneswaran, Darlene J Elias, John H Griffin

Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target

多发性骨髓瘤相关的 hDIS3 突变导致细胞 RNA 代谢紊乱,并表明 hDIS3 PIN 结构域可作为潜在的药物靶点

Rafal Tomecki, Karolina Drazkowska, Iwo Kucinski, Krystian Stodus, Roman J Szczesny, Jakub Gruchota, Ewelina P Owczarek, Katarzyna Kalisiak, Andrzej Dziembowski