日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TEAD-targeting small molecules induce a cofactor switch to regulate the Hippo pathway

靶向TEAD的小分子诱导辅因子转换,从而调节Hippo通路。

Guarnaccia, Alissa D; Hagenbeek, Thijs J; Lee, Wendy; Kljavin, Noelyn; Choi, Meena; Tombling, Benjamin; Peukert, Carsten; Ulas, Gözde; Kameswaran, Vasumathi; Le, Daniel; Paul, Sayantanee; Vaidya, Samir; Zbieg, Jason R; Crawford, James J; Daniel, Bence; Dey, Anwesha; Lill, Jennie R

Interferon regulatory factor 4 mediates nonenzymatic IRE1 dependency in multiple myeloma cells.

干扰素调节因子 4 介导多发性骨髓瘤细胞中非酶促 IRE1 依赖性

Oikonomidi Ioanna, Kameswaran Vasumathi, Pham Victoria C, Zuazo-Gaztelu Iratxe, Gutgesell Lauren M, Marsters Scot, Daniel Bence, Lill Jennie R, Modrusan Zora, Ashkenazi Avi

Modeling congenital heart disease: lessons from mice, hPSC-based models, and organoids

先天性心脏病建模:来自小鼠、基于hPSC的模型和类器官的经验教训

Rao, Kavitha S; Kameswaran, Vasumathi; Bruneau, Benoit G

Targeted demethylation at the CDKN1C/p57 locus induces human β cell replication

CDKN1C/p57基因座的靶向去甲基化诱导人β细胞复制

Ou, Kristy; Yu, Ming; Moss, Nicholas G; Wang, Yue J; Wang, Amber W; Nguyen, Son C; Jiang, Connie; Feleke, Eseye; Kameswaran, Vasumathi; Joyce, Eric F; Naji, Ali; Glaser, Benjamin; Avrahami, Dana; Kaestner, Klaus H

The Dysregulation of the DLK1-MEG3 Locus in Islets From Patients With Type 2 Diabetes Is Mimicked by Targeted Epimutation of Its Promoter With TALE-DNMT Constructs

利用TALE-DNMT构建体对DLK1-MEG3基因座启动子进行靶向表观突变,可以模拟2型糖尿病患者胰岛中DLK1-MEG3基因座的失调。

Kameswaran, Vasumathi; Golson, Maria L; Ramos-Rodríguez, Mireia; Ou, Kristy; Wang, Yue J; Zhang, Jia; Pasquali, Lorenzo; Kaestner, Klaus H

The Missing lnc(RNA) between the pancreatic β-cell and diabetes

胰岛β细胞与糖尿病之间缺失的lnc(RNA)

Kameswaran, Vasumathi; Kaestner, Klaus H

Mechanisms of plasma membrane targeting of formin mDia2 through its amino terminal domains

formin mDia2 通过其氨基末端结构域靶向质膜的机制

Gorelik, Roman; Yang, Changsong; Kameswaran, Vasumathi; Dominguez, Roberto; Svitkina, Tatyana