日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Naphthoquinone-derived tridentate Ru(II) and Os(II) organometallics with exceptional cytotoxicity: synthesis, characterization, stability in aqueous solution and biological in vitro evaluation

萘醌衍生的三齿Ru(II)和Os(II)有机金属化合物具有优异的细胞毒性:合成、表征、水溶液稳定性及体外生物学评价

Rosner, Alexander; Geisler, Heiko; Hejl, Michaela; Gradl, Mathias; Legin, Anton A; Prado-Roller, Alexander; Jakupec, Michael A; Heffeter, Petra; Berger, Walter; Keppler, Bernhard K; Kandioller, Wolfgang

Selectivity for TP53 signalling drives the mode of action of a highly potent N,O,O-tridentate naphthoquinone-based organo-ruthenium anticancer drug candidate

一种高效的基于N,O,O-三齿萘醌的有机钌抗癌候选药物的作用机制取决于其对TP53信号通路的选择性。

Rosner, Alexander; Skos, Lukas; Mendrina, Theresa; Baier, Dina; Hejl, Michaela; Borutzki, Yasmin; Gradl, Mathias; Geisler, Heiko; Mohr, Thomas; Legin, Anton; Jakupec, Michael A; Bileck, Andrea; Gerner, Christopher; Koellensperger, Gunda; Heffeter, Petra; Berger, Walter; Keppler, Bernhard K; Kandioller, Wolfgang; Meier-Menches, Samuel M

Exploring the Anticancer Properties of 4-Phenylthiazole-Based Ru(II) and Os(II) Metallacycles Featuring 1-Methylimidazole as N-Donor Functionality

探索以1-甲基咪唑为N-供体官能团的4-苯基噻唑基Ru(II)和Os(II)金属环的抗癌特性

Getreuer, Paul; Mendrina, Theresa; van Terwingen, Steven; Marretta, Laura; Dömötör, Orsolya; Wenisch, Dominik; Hejl, Michaela; Heffeter, Petra; Berger, Walter; Jakupec, Michael A; Terenzi, Alessio; Keppler, Bernhard K; Kandioller, Wolfgang

Amide-to-Triazole Switch in Somatostatin-14-Based Radioligands: Impact on Receptor Affinity and In Vivo Stability

生长抑素-14 基放射性配体中的酰胺到三唑转换:对受体亲和力和体内稳定性的影响

Xabier Guarrochena, Panagiotis Kanellopoulos, Anna Stingeder, Lisa-Maria Rečnik, Irene V J Feiner, Marie Brandt, Wolfgang Kandioller, Theodosia Maina, Berthold A Nock, Thomas L Mindt

Di-[trioctyl-(8-phenyloctyl)-phosphonium] pamoate: synthesis and characterization of a novel, highly hydrophobic ionic liquid for the extraction of scandium, thorium and uranium

二-[三辛基-(8-苯基辛基)-膦]帕莫酸盐:一种新型高疏水性离子液体的合成与表征及其在钪、钍和铀萃取中的应用

Gradwohl, Andreas; Windisch, Jakob; Rosner, Alexander; Heninger, Julia; Fuhrmann, Philipp L; Wallner, Gabriele; Keppler, Bernhard K; Kandioller, Wolfgang; Jirsa, Franz

Synthesis and Preclinical Evaluation of Radiolabeled [(103)Ru]BOLD-100

放射性标记的[(103)Ru]BOLD-100的合成及临床前评价

Happl, Barbara; Brandt, Marie; Balber, Theresa; Benčurová, Katarína; Talip, Zeynep; Voegele, Alexander; Heffeter, Petra; Kandioller, Wolfgang; Van der Meulen, Nicholas P; Mitterhauser, Markus; Hacker, Marcus; Keppler, Bernhard K; Mindt, Thomas L

Half-Sandwich Rhodium Complexes with Releasable N-Donor Monodentate Ligands: Solution Chemical Properties and the Possibility for Acidosis Activation

具有可释放 N 供体单齿配体的半夹心铑配合物:溶液化学性质和激活酸中毒的可能性

János P Mészáros, Wolfgang Kandioller, Gabriella Spengler, Alexander Prado-Roller, Bernhard K Keppler, Éva A Enyedy

Anticancer Tungstenocenes with a Diverse Set of (O,O-), (O, S-) and (O, N-) Chelates-A Detailed Biological Study Using an Improved Evaluation via 3D Spheroid Models

具有多种 (O,O-)、(O, S-) 和 (O, N-) 螯合物的抗癌钨二茂物 - 使用通过 3D 球体模型改进的评估方法进行的详细生物学研究

Klaudia Cseh, Iker Berasaluce, Valentin Fuchs, Alexandra Banc, Andreas Schweikert, Alexander Prado-Roller, Michaela Hejl, Debora Wernitznig, Gunda Koellensperger, Michael A Jakupec, Wolfgang Kandioller, Michael S Malarek, Bernhard K Keppler

Extraction of rare earth elements from aqueous solutions using the ionic liquid trihexyltetradecylphosphonium 3-hydroxy-2-naphthoate

利用离子液体三己基十四烷基膦3-羟基-2-萘甲酸从水溶液中萃取稀土元素

Gradwohl, Andreas; Windisch, Jakob; Weissensteiner, Matthias; Keppler, Bernhard K; Kandioller, Wolfgang; Jirsa, Franz

Arene Variation of Highly Cytotoxic Tridentate Naphthoquinone-Based Ruthenium(II) Complexes and In-Depth In Vitro Studies

高细胞毒性三齿萘醌基钌(II)配合物的芳烃变体及深入的体外研究

Klaudia Cseh, Heiko Geisler, Kristina Stanojkovska, Julia Westermayr, Philipp Brunmayr, Dominik Wenisch, Natalie Gajic, Michaela Hejl, Martin Schaier, Gunda Koellensperger, Michael A Jakupec, Philipp Marquetand, Wolfgang Kandioller