日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery of a potent anti-Zika virus benzamide series targeting the viral protein NS4B

发现一系列靶向病毒蛋白NS4B的强效抗寨卡病毒苯甲酰胺类化合物

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1013609
Chung, Donghoon; Otsuka, Yuka; Kim, Eunjung; Ullah, Sultan; Kennedy, Nicole M; Ngo, Khac Huy; Kang, Jinjoo; Tomlinson, Reece; Alejandro, Brian; Barnaby, Koji; Miller, Jeffrey; Shumate, Justin; Teo, Chwee Fang; Tan, Yaw Bia; Chew, Che Shin; Kang, CongBao; Luo, Dahai; Scampavia, Louis; Spicer, Timothy P; Bannister, Thomas D
微生物学
发表日期：2026
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Discovery of Pan-TEAD Inhibitors That Disrupt YAP-TEAD Interaction as a Potential Therapy for Gastric Cancers and Mutant KRAS and EGFR Lung Cancers

发现可破坏YAP-TEAD相互作用的泛TEAD抑制剂，有望成为胃癌以及KRAS和EGFR突变型肺癌的潜在疗法

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.5c00590
Kumar, Ramesh; Thian, Joanne; Toh, Joel D W; Farzana, Noorul; Sun, Jialin; Kang, CongBao; Low, Suet Mei Crystal; Wee, Sheena; Lim, Zijie; Gunaratne, Jayantha; Loh, Hui Mun; Kannan, Srinivasaraghavan; Verma, Chandra S; Chakraborty, Sayan; Hong, Wanjin
EGFR
胃癌
RAS
YAP
肺癌
肿瘤
EGF
肿瘤免疫
发表日期：2026
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Entry Inhibitors of SARS-CoV-2 Targeting the Transmembrane Domain of the Spike Protein.

针对SARS-CoV-2刺突蛋白跨膜结构域的入侵抑制剂

期刊:Viruses-Basel
影响因子:3.5
doi:10.3390/v17070989
Lyles Kristin V, Stone Shannon, Singh Priti, Patterson Lila D, Natekar Janhavi, Pathak Heather, Varshnaya Rohit K, Elsharkawy Amany, Liu Dongning, Bansal Shubham, Faniyi Oluwafoyinsola O, Tang Sijia, Yang Xiaoxiao, Mulpuri Nagaraju, Hamelberg Donald, Kang Congbao, Wang Binghe, Kumar Mukesh, Luo Ming
炎症/感染
新冠
发表日期：2025
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Discovery of a potent anti-Zika virus benzamide series targeting the viral protein NS4B

发现一系列靶向病毒蛋白NS4B的强效抗寨卡病毒苯甲酰胺类化合物

期刊:
影响因子:
doi:10.1101/2025.10.09.681361
Chung, Donghoon; Otsuka, Yuka; Kim, Eunjung; Ullah, Sultan; Kennedy, Nicole M; Ngo, Khac Huy; Kang, Jinjoo; Tomlison, Reece; Alejandro, Brian; Barnaby, Koji; Miller, Jeffery; Shumate, Justin; Teo, Chwee Fang; Tan, Yaw Bia; Chew, Che Shin; Kang, CongBao; Luo, Dahai; Scampavia, Louis; Spicer, Timothy P; Bannister, Thomas D
微生物学
发表日期：2025
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Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening

通过基于片段的筛选鉴定泛素结合酶UBE2T的小分子结合位点

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.4904
Loh, Yong Yao; Anantharajan, Jothi; Huang, Qiwei; Xu, Weijun; Fulwood, Justina; Ng, Hui Qi; Ng, Elizabeth Yihui; Gea, Chong Yu; Choong, Meng Ling; Tan, Qian Wen; Koh, Xiaoying; Lim, Wan Hsin; Nacro, Kassoum; Cherian, Joseph; Baburajendran, Nithya; Ke, Zhiyuan; Kang, CongBao
UBE2T
发表日期：2024
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Perspectives on Applications of (19)F-NMR in Fragment-Based Drug Discovery

（19）F-NMR在基于片段的药物发现中的应用展望

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules29235748
Li, Qingxin; Kang, CongBao
发表日期：2024
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A high-throughput cell-based screening method for Zika virus protease inhibitor discovery.

一种用于发现寨卡病毒蛋白酶抑制剂的高通量细胞筛选方法

期刊:SLAS Discovery
影响因子:2.7
doi:10.1016/j.slasd.2024.100164
Anindita Paulina Duhita, Otsuka Yuka, Lattmann Simon, Ngo Khac Huy, Liew Chong Wai, Kang CongBao, Harris Reuben S, Scampavia Louis, Spicer Timothy P, Luo Dahai
细胞生物学
发表日期：2024
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Targeted Degradation of XIAP is Sufficient and Specific to Induce Apoptosis in MYCN-overexpressing High-risk Neuroblastoma

靶向降解XIAP足以且特异性地诱导MYCN过表达的高危神经母细胞瘤细胞凋亡

期刊:Cancer Research Communications
影响因子:3.3
doi:10.1158/2767-9764.CRC-23-0082
Choo, Zhang'E; Koh, Xiaoying; Wong, Megan Rui En; Ashokan, Ruth Minothini; Ali Ahamed, Nurul Suhana Binte; Kang, CongBao; Kuick, Chik Hong; Chang, Kenneth Tou En; Larisch, Sarit; Loh, Amos Hong Pheng; Chen, Zhi Xiong
凋亡
表观遗传
细胞生物学
Apoptosis
XIAP
MYC
发表日期：2023
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Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase

EYA2酪氨酸磷酸酶变构抑制剂的构效关系研究

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.4234
Anantharajan, Jothi; Baburajendran, Nithya; Lin, Grace; Loh, Yong Yao; Xu, Weijun; Ahmad, Nur Huda Binte; Liu, Shuang; Jansson, Anna E; Kuan, John Wee Liang; Ng, Elizabeth Yihui; Yeo, Yee Khoon; Hung, Alvin W; Joy, Joma; Hill, Jeffrey; Ford, Heide L; Zhao, Rui; Keller, Thomas H; Kang, CongBao
发表日期：2022
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Secondary Structures of the Transmembrane Domain of SARS-CoV-2 Spike Protein in Detergent Micelles

SARS-CoV-2刺突蛋白跨膜结构域在去垢剂胶束中的二级结构

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms23031040
Li, Qingxin; Huang, Qiwei; Kang, Congbao
SARS-CoV-2
发表日期：2022
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