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Discovery of highly immunogenic spleen-resident FCGR3(+)CD103(+) cDC1s differentiated by IL-33-primed ST2(+) basophils

发现由IL-33启动的ST2(+)嗜碱性粒细胞分化而来的脾脏驻留高免疫原性FCGR3(+)CD103(+) cDC1s

Kang, Myeong-Ho; Hong, JungHyub; Lee, Jinjoo; Cha, Min-Suk; Lee, Sangho; Kim, Hye-Young; Ha, Sang-Jun; Lim, Yong Taik; Bae, Yong-Soo

IL-3

Epitranscriptomic Approach: To Improve the Efficacy of ICB Therapy by Co-Targeting Intracellular Checkpoint CISH

表观转录组学方法：通过联合靶向细胞内检查点CISH提高ICB疗法的疗效

期刊:Cells

影响因子:5.2

doi:10.3390/cells10092250

Kumar, Sunil; Sarthi, Parth; Mani, Indra; Ashraf, Muhammad Umer; Kang, Myeong-Ho; Kumar, Vishal; Bae, Yong-Soo

SH2 domain-containing adaptor protein B expressed in dendritic cells is involved in T-cell homeostasis by regulating dendritic cell-mediated Th2 immunity

树突状细胞表达的含SH2结构域的衔接蛋白B通过调节树突状细胞介导的Th2免疫参与T细胞稳态。

期刊:Clinical and Experimental Vaccine Research

影响因子:1.3

doi:10.7774/cevr.2017.6.1.50

Ahmed, Md Selim; Kang, Myeong-Ho; Lee, Ezra; Park, Yujin; Jeong, Yideul; Bae, Yong-Soo

Azasugar-containing phosphorothioate oligonucleotide (AZPSON) DBM-2198 inhibits human immunodeficiency virus type 1 (HIV-1) replication by blocking HIV-1 gp120 without affecting the V3 region.

含氮杂糖的硫代磷酸酯寡核苷酸 (AZPSON) DBM-2198 通过阻断 HIV-1 gp120 抑制人类免疫缺陷病毒 1 型 (HIV-1) 的复制，而不影响 V3 区

期刊:Molecules and Cells

影响因子:6.5

doi:10.14348/molcells.2015.2129

Lee Jinjoo, Byeon Se Eun, Jung Ju Yeol, Kang Myeong-Ho, Park Yu-Jin, Jung Kyeong-Eun, Bae Yong-Soo

IL-33 and IL-33-derived DC-based tumor immunotherapy

IL-33 和 IL-33 衍生的基于树突状细胞的肿瘤免疫疗法

Discovery of highly immunogenic spleen-resident FCGR3(+)CD103(+) cDC1s differentiated by IL-33-primed ST2(+) basophils

发现由IL-33启动的ST2(+)嗜碱性粒细胞分化而来的脾脏驻留高免疫原性FCGR3(+)CD103(+) cDC1s

Epitranscriptomic Approach: To Improve the Efficacy of ICB Therapy by Co-Targeting Intracellular Checkpoint CISH

表观转录组学方法：通过联合靶向细胞内检查点CISH提高ICB疗法的疗效

SH2 domain-containing adaptor protein B expressed in dendritic cells is involved in T-cell homeostasis by regulating dendritic cell-mediated Th2 immunity

树突状细胞表达的含SH2结构域的衔接蛋白B通过调节树突状细胞介导的Th2免疫参与T细胞稳态。

Azasugar-containing phosphorothioate oligonucleotide (AZPSON) DBM-2198 inhibits human immunodeficiency virus type 1 (HIV-1) replication by blocking HIV-1 gp120 without affecting the V3 region.

含氮杂糖的硫代磷酸酯寡核苷酸 (AZPSON) DBM-2198 通过阻断 HIV-1 gp120 抑制人类免疫缺陷病毒 1 型 (HIV-1) 的复制，而不影响 V3 区