Design of Bicyclic Peptide Tandems Mimicking the Homodimeric GDF15 Protein to Inhibit GDF15-GFRaL-RET Complex Cell Signaling
设计模拟同源二聚体GDF15蛋白的双环肽串联体以抑制GDF15-GFRaL-RET复合物细胞信号传导
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c01378
Noisier, Anaïs F M; Sandmark, Jenny; Edfeldt, Fredrik; Backmark, Anna; Broddefalk, Johan; Wandzik, Joanna; Jurva, Ulrik; Ek, Margareta; Johansson, Carina A; Barlind, Louise; Gunnarsson, Jenny; Bigalke, Janna M; Xue, Yafeng; Frolov, Andrey I; Kankkonen, Cecilia; Roth, Robert G; Fritsch, Maria; Watcham, Sophie; van Rietschoten, Katerine; Mudd, Gemma E; Harrison, Helen; Chen, Liuhong; Skynner, Michael J; Craik, David J; Chankeshwara, Sunay V; Lemurell, Malin
