The mutation L69P in the PAS domain of the hERG potassium channel results in LQTS by trafficking deficiency
hERG钾通道PAS结构域中的L69P突变会导致转运缺陷,进而引发长QT综合征(LQTS)。
期刊:Channels
影响因子:3.2
doi:10.1080/19336950.2020.1751522
Jenewein, Tina; Kanner, Scott A; Bauer, Daniel; Hertel, Brigitte; Colecraft, Henry M; Moroni, Anna; Thiel, Gerhard; Kauferstein, Silke