日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cell-specific DNA methylation in human alpha and beta cells regulates gene expression in type 2 diabetes

人类α细胞和β细胞中的细胞特异性DNA甲基化调控2型糖尿病中的基因表达

Ofori, Jones K; Ruhrmann, Sabrina; Lindström, Axel; Perfilyev, Alexander; Martin, Melina; Karagiannopoulos, Alexandros; Scisciola, Lucia; Kost, Katja; Jönsson, Josefine; Nilsson, Åsa; Kantor, Boris; Dudenhöffer-Pfeifer, Monika; Rots, Marianne G; Wendt, Anna; Rönn, Tina; Eliasson, Lena; Bacos, Karl; Ling, Charlotte

CRISPR-Cas editing technologies for viral-mediated gene therapies of human diseases: Mechanisms, progress, and challenges

CRISPR-Cas基因编辑技术在病毒介导的人类疾病基因治疗中的应用:机制、进展与挑战

Kantor, Boris; Duke, Leanne; Bhide, Pradeep G

Trends and challenges of AAV-delivered gene editing therapeutics for CNS disorders: Implications for neurodegenerative disease

AAV递送基因编辑疗法治疗中枢神经系统疾病的趋势与挑战:对神经退行性疾病的启示

Kantor, Boris; O'Donovan, Bernadette; Chiba-Falek, Ornit

SNCA -targeted epigenome therapy for Parkinson's disease alleviates pathological and behavioral perturbations in a mouse model.

针对帕金森病的 SNCA 靶向表观基因组疗法可减轻小鼠模型中的病理和行为紊乱

O'Donovan Bernadette, Rittiner Joseph, Upadhya Suraj, Hodgson Dellila, Kantor Boris, Chiba-Falek Ornit

Therapeutic modulation of gene expression in the disease state: Treatment strategies and approaches for the development of next-generation of the epigenetic drugs

疾病状态下基因表达的治疗性调控:治疗策略和下一代表观遗传药物的研发途径

Rittiner, Joseph; Cumaran, Mohanapriya; Malhotra, Sahil; Kantor, Boris

APOE: The New Frontier in the Development of a Therapeutic Target towards Precision Medicine in Late-Onset Alzheimer's

APOE:晚发性阿尔茨海默病精准治疗靶点开发的新前沿

Yang, Anna; Kantor, Boris; Chiba-Falek, Ornit

Lentiviral Vectors for Delivery of Gene-Editing Systems Based on CRISPR/Cas: Current State and Perspectives

基于CRISPR/Cas的基因编辑系统的慢病毒载体:现状与展望

Dong, Wendy; Kantor, Boris

Cell-Type Specific Changes in DNA Methylation of SNCA Intron 1 in Synucleinopathy Brains

突触核蛋白病脑组织中SNCA内含子1 DNA甲基化的细胞类型特异性改变

Gu, Jeffrey; Barrera, Julio; Yun, Young; Murphy, Susan K; Beach, Thomas G; Woltjer, Randy L; Serrano, Geidy E; Kantor, Boris; Chiba-Falek, Ornit

Gene-Editing Technologies Paired With Viral Vectors for Translational Research Into Neurodegenerative Diseases

基因编辑技术与病毒载体相结合,用于神经退行性疾病的转化研究

Rittiner, Joseph Edward; Moncalvo, Malik; Chiba-Falek, Ornit; Kantor, Boris

Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models.

用于将表观基因组编辑工具高效递送至人类诱导多能干细胞衍生疾病模型的慢病毒载体平台

Tagliafierro Lidia, Ilich Ekaterina, Moncalvo Malik, Gu Jeffrey, Sriskanda Ahila, Grenier Carole, Murphy Susan K, Chiba-Falek Ornit, Kantor Boris