Deletion of SPI1 in microglia exacerbates amyloid pathology by impairing microglial response in Alzheimer's disease models.
在阿尔茨海默病模型中，小胶质细胞中 SPI1 的缺失会损害小胶质细胞的反应，从而加剧淀粉样蛋白病理。
期刊:Neuron
影响因子:15
doi:10.1016/j.neuron.2026.03.011
Kim Byungwook, Tate Mason Douglas, Karahan Hande, Wijeratne H R Sagara, Sharify Ahmad Daniel, Wang Selena S, Kim Justin R, Al-Amin Md Mamun, Hartigan Kelly, Chung Sunwoo, Dabin Luke Child, Acri Dominic J, Doud Emma H, John Sutha K, Mosley Amber L, Kim Jungsu
