日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Conformational landscape and clustering of human type 2 IP(3) receptor in lipid nanodiscs

脂质纳米盘中人2型IP(3)受体的构象景观和聚集

Liu, Caifeng; Lan, Yu-Jing; Tang, Qingyu; Karakas, Erkan

A conserved mechanism of LRRC8 channel inhibition by two structurally distinct drugs

两种结构不同的药物对LRRC8通道抑制的保守机制

Yamada, Toshiki; Bisignano, Paola; Karakas, Erkan; Denton, Jerod S

Recent advances in structural characterization of volume-regulated anion channels (VRACs)

体积调节阴离子通道(VRAC)结构表征的最新进展

Karakas, Erkan; Strange, Kevin; Denton, Jerod S

Conformational cycle of a protease-containing ABC transporter in lipid nanodiscs reveals the mechanism of cargo-protein coupling

脂质纳米盘中含蛋白酶ABC转运蛋白的构象循环揭示了货物-蛋白偶联机制

Zhang, Ruojing; Jagessar, Kevin L; Brownd, Matthew; Polasa, Adithya; Stein, Richard A; Moradi, Mahmoud; Karakas, Erkan; Mchaourab, Hassane S

Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter

不对称构象和脂质相互作用塑造了异二聚体ABC转运蛋白的ATP偶联循环

Tang, Qingyu; Sinclair, Matt; Hasdemir, Hale S; Stein, Richard A; Karakas, Erkan; Tajkhorshid, Emad; Mchaourab, Hassane S

Cryo-EM structures of an LRRC8 chimera with native functional properties reveal heptameric assembly.

具有天然功能特性的 LRRC8 嵌合体的冷冻电镜结构揭示了七聚体组装

Takahashi Hirohide, Yamada Toshiki, Denton Jerod S, Strange Kevin, Karakas Erkan

Structural basis for activation and gating of IP(3) receptors

IP(3)受体激活和门控的结构基础

Schmitz, Emily A; Takahashi, Hirohide; Karakas, Erkan

Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist

人3型肌醇三磷酸受体的冷冻电镜结构揭示了一种自身结合肽的存在,该肽可作为拮抗剂发挥作用。

Azumaya, Caleigh M; Linton, Emily A; Risener, Caitlin J; Nakagawa, Terunaga; Karakas, Erkan

Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.

NMDA受体基因剪接功能调控的结构机制

Regan Michael C, Grant Timothy, McDaniel Miranda J, Karakas Erkan, Zhang Jing, Traynelis Stephen F, Grigorieff Nikolaus, Furukawa Hiro

Emerging structural insights into the function of ionotropic glutamate receptors

离子型谷氨酸受体功能结构研究的新进展

Karakas, Erkan; Regan, Michael C; Furukawa, Hiro