日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Interpreting the functional impact of genetic variants: The need for context qualifiers

解读基因变异的功能影响:需要上下文限定词

Martinelli, Simone; Cavé, Hélène; De Luca, Alessandro; DiStefano, Marina; Karchin, Rachel; Lugones, Ana Clara; O'Donnell-Luria, Anne; Ritter, Deborah I; Tamborero, David; Tolstorukov, Michael Y; Campregher, Paulo Vidal; Tartaglia, Marco; Sonkin, Dmitriy

Reconstructing clone-resolved transcriptional programs from bulk tumor sequencing

从肿瘤整体测序数据中重建克隆分辨的转录程序

Lai, Jiaying; Yang, Yi; Noller, Kathleen; Liu, Yunzhou; Balan, Archana; Nagendra, Prathima B; Kagohara, Luciane T; Fertig, Elana J; Wood, Laura D; Karchin, Rachel

Deep Learning Enabled 3D Multi-Omic Analysis Reveals Molecular Signatures of Heterogeneous Response to Chemotherapy in Pancreatic Cancer

深度学习赋能的三维多组学分析揭示胰腺癌化疗异质性反应的分子特征

Forjaz, André; Mojdeganlou, Hengameh; Valentin, Alens; Wetzel, Meredith; Lvovs, Dmitrijs; Deshpande, Atul; Shin, Sarah M; Piya, Sujan; Rajapakshe, Kimal I; Guerrero, Paola A; Pedro, Brian A; Sidiropoulos, Dimitrios N; Wu, Pei-Hsun; Pagan, Vincent Bernard; Wirtz, Denis; Fertig, Elana J; Kagohara, Luciane T; Ho, Won Jin; Kiemen, Ashley L; Wood, Laura D; Christenson, Eric S; Freed-Pastor, William A; Iacobuzio-Donahue, Christine A; Karchin, Rachel; Karnoub, Elias-Ramzey; Maitra, Anirban; Melchor, Jerry; Park, Wungki; Matos-Romero, Valentina; O'Reilly, Eileen; Soares, Kevin C

Combination of pembrolizumab and radiotherapy induces systemic antitumor immune responses in immunologically cold non-small cell lung cancer

帕博利珠单抗联合放疗可诱导免疫冷型非小细胞肺癌产生全身性抗肿瘤免疫反应

Huang, Justin; Theelen, Willemijn S M E; Belcaid, Zineb; Najjar, Mimi; van der Geest, Daphne; Singh, Dipika; Cherry, Christopher; Balan, Archana; White, James R; Wehr, Jaime; Karchin, Rachel; Niknafs, Noushin; van den Heuvel, Michel M; Velculescu, Victor E; Smith, Kellie N; Baas, Paul; Anagnostou, Valsamo

Informatics at the Frontier of Cancer Research

癌症研究前沿的信息学

Noller, Kathleen; Botsis, Taxiarchis; Camara, Pablo G; Ciotti, Lauren; Cooper, Lee A D; Goecks, Jeremy; Griffith, Malachi; Haas, Brian J; Ideker, Trey; Karchin, Rachel; Kontos, Despina; Lai, Jiaying; Marcus, Daniel; Meyer, Clifford A; Naegle, Kristen; Pati, Sarthak; Peters, Bjoern; Pratt, Dexter; Raphael, Benjamin J; Reich, Michael; Savova, Guergana K; Wright, Carrie; Fertig, Elana J; Bakas, Spyridon

Proteome-wide assessment of differential missense variant clustering in neurodevelopmental disorders and cancer

对神经发育障碍和癌症中差异性错义变异聚类的蛋白质组学评估

Ng, Jeffrey K; Chen, Yilin; Akinwe, Titilope M; Heins, Hillary B; Mehinovic, Elvisa; Chang, Yoonhoo; Gutmann, David H; Gurnett, Christina A; Payne, Zachary L; Manuel, Juana G; Karchin, Rachel; Turner, Tychele N

Spatial proteomics and transcriptomics reveal early immune cell organization in pancreatic intraepithelial neoplasia.

空间蛋白质组学和转录组学揭示了胰腺上皮内瘤变早期免疫细胞的组织结构

Lyman Melissa R, Mitchell Jacob T, Raghavan Sidharth, Kagohara Luciane T, Huff Amanda L, Haldar Saurav D, Shin Sarah M, Guinn Samantha, Barrett Benjamin, Longway Gabriella, Hernandez Alexei, Coyne Erin M, Yuan Xuan, Andaloori Lalitya, Lai Jiaying, Liu Yun Zhou, Karchin Rachel, Gupta Anuj, Kiemen Ashley L, Forjaz André, Wirtz Denis, Wu Pei-Hsun, Deshpande Atul, Lee Jae W, Armstrong Todd D, Azad Nilofer S, Zimmerman Jacquelyn W, Wood Laura D, Anders Robert A, Thompson Elizabeth D, Jaffee Elizabeth M, Fertig Elana J, Ho Won Jin, Zaidi Neeha

Integrative analysis of genomic and transcriptomic data informs precancer progression in the pancreas

基因组和转录组数据的整合分析有助于了解胰腺癌前病变的进展

Noller, Kathleen; Lai, Jiaying; Lesperance, Daniel; Adkins, Ricky S; Elhossiny, Ahmed; Guerrero, Paola A; Rajapakshe, Kimal I; Maitra, Anirban; Giglio, Michelle; Mahurkar, Anup; White, Owen; Di Magliano, Marina Pasca; Ochs, Michael F; Kagohara, Luciane T; Wood, Laura D; Karchin, Rachel; Fertig, Elana J

Improving transparency of computational tools for variant effect prediction

提高变异效应预测计算工具的透明度

Karchin, Rachel; Radivojac, Predrag; O'Donnell-Luria, Anne; Greenblatt, Marc S; Tolstorukov, Michael Y; Sonkin, Dmitriy

SpliceMutr Enables Pan-Cancer Analysis of Splicing-Derived Neoantigen Burden in Tumors

SpliceMutr能够对肿瘤中剪接衍生的新抗原负荷进行泛癌分析

Palmer, Theron; Kessler, Michael D; Shao, Xiaoshan M; Balan, Archana; Yarchoan, Mark; Zaidi, Neeha; Lopez-Vidal, Tamara Y; Saeed, Ali M; Gore, Jessica; Azad, Nilofer S; Jaffee, Elizabeth M; Favorov, Alexander V; Anagnostou, Valsamo; Karchin, Rachel; Gaykalova, Daria A; Fertig, Elana J; Danilova, Ludmila