日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Orally active MMP-1 sparing α-tetrahydropyranyl and α-piperidinyl sulfone matrix metalloproteinase (MMP) inhibitors with efficacy in cancer, arthritis, and cardiovascular disease

口服活性 MMP-1 保留 α-四氢吡喃基和 α-哌啶基砜基质金属蛋白酶 (MMP) 抑制剂,可有效治疗癌症、关节炎和心血管疾病

Daniel P Becker, Thomas E Barta, Louis J Bedell, Terri L Boehm, Brian R Bond, Jeffery Carroll, Chris P Carron, Gary A Decrescenzo, Alan M Easton, John N Freskos, Chris L Funckes-Shippy, Marcia Heron, Susan Hockerman, Carol Pearcy Howard, James R Kiefer, Madeleine H Li, Karl J Mathis, Joseph J McDona

Structural and inhibition analysis reveals the mechanism of selectivity of a series of aggrecanase inhibitors

结构和抑制分析揭示了一系列聚集蛋白聚糖酶抑制剂的选择性机制

Micky D Tortorella, Alfredo G Tomasselli, Karl J Mathis, Mark E Schnute, Scott S Woodard, Grace Munie, Jennifer M Williams, Nicole Caspers, Arthur J Wittwer, Anne-Marie Malfait, Huey-Sheng Shieh