TRAIL induces cytokine production via the NFkB2 pathway promoting neutrophil chemotaxis and neutrophil-mediated immune-suppression in triple negative breast cancer cells
TRAIL通过NF-κB2通路诱导细胞因子产生,促进中性粒细胞趋化和中性粒细胞介导的免疫抑制,从而增强三阴性乳腺癌细胞的免疫活性。
期刊:Cancer Letters
影响因子:10.1
doi:10.1016/j.canlet.2025.217692
Kundu, Manjari; Greer, Yoshimi E; Lobanov, Alexei; Ridnour, Lisa; Donahue, Renee N; Ng, Yeap; Ratnayake, Shashi; White, Karley; Voeller, Donna; Weltz, Sarah; Chen, Qingrong; Lockett, Stephen J; Cam, Maggie; Meerzaman, Daoud; Wink, David A; Weigert, Roberto; Lipkowitz, Stanley
肿瘤
中性粒细胞
肿瘤免疫
信号转导
乳腺癌
粒细胞
TRAIL
细胞生物学
免疫/内分泌