日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reactive Oxygen Species in the Adverse Outcome Pathway Framework: Toward Creation of Harmonized Consensus Key Events

活性氧在不良结局路径框架中的作用:迈向建立统一共识的关键事件

Tanabe, Shihori; O'Brien, Jason; Tollefsen, Knut Erik; Kim, Youngjun; Chauhan, Vinita; Yauk, Carole; Huliganga, Elizabeth; Rudel, Ruthann A; Kay, Jennifer E; Helm, Jessica S; Beaton, Danielle; Filipovska, Julija; Sovadinova, Iva; Garcia-Reyero, Natalia; Mally, Angela; Poulsen, Sarah Søs; Delrue, Nathalie; Fritsche, Ellen; Luettich, Karsta; La Rocca, Cinzia; Yepiskoposyan, Hasmik; Klose, Jördis; Danielsen, Pernille Høgh; Esterhuizen, Maranda; Jacobsen, Nicklas Raun; Vogel, Ulla; Gant, Timothy W; Choi, Ian; FitzGerald, Rex

Assessment of inhalation toxicity of cigarette smoke and aerosols from flavor mixtures: 5-week study in A/J mice

香烟烟雾和香精混合物气溶胶吸入毒性评估:对 A/J 小鼠进行为期 5 周的研究

Ee Tsin Wong, Karsta Luettich, Lydia Cammack, Chin Suan Chua, David Sciuscio, Celine Merg, Maica Corciulo, Romain Piault, Kumar Ashutosh, Cameron Smith, Patrice Leroy, Fabian Moine, Anneke Glabasnia, Pierrick Diana, Cecilia Chia, Ching Keong Tung, Nikolai Ivanov, Julia Hoeng, Manuel Peitsch, Kyeongh

Effects of cigarette smoke exposure on a mouse model of multiple sclerosis

香烟烟雾暴露对多发性硬化症小鼠模型的影响

Ho, Jenny; Koshibu, Kyoko; Xia, Wenhao; Luettich, Karsta; Kondylis, Athanasios; Garcia, Llenalia; Phillips, Blaine; Peitsch, Manuel; Hoeng, Julia

An Adverse Outcome Pathway for Decreased Lung Function Focusing on Mechanisms of Impaired Mucociliary Clearance Following Inhalation Exposure

吸入暴露后黏液纤毛清除功能受损机制与肺功能下降不良结局通路

Luettich, Karsta; Sharma, Monita; Yepiskoposyan, Hasmik; Breheny, Damien; Lowe, Frazer J

Development of an Advanced Multicellular Intestinal Model for Assessing Immunomodulatory Properties of Anti-Inflammatory Compounds

开发先进的多细胞肠道模型来评估抗炎化合物的免疫调节特性

Diego Marescotti, Giuseppe Lo Sasso, Diego Guerrera, Kasper Renggli, Pedro A Ruiz Castro, Romain Piault, Vincent Jaquet, Fabian Moine, Karsta Luettich, Stefan Frentzel, Manuel C Peitsch, Julia Hoeng

Discriminating Spontaneous From Cigarette Smoke and THS 2.2 Aerosol Exposure-Related Proliferative Lung Lesions in A/J Mice by Using Gene Expression and Mutation Spectrum Data

利用基因表达和突变谱数据区分 A/J 小鼠自发性增生性肺病变与香烟烟雾和 THS 2.2 气溶胶暴露相关增生性肺病变

Yang Xiang, Karsta Luettich, Florian Martin, James N D Battey, Keyur Trivedi, Laurent Neau, Ee Tsin Wong, Emmanuel Guedj, Remi Dulize, Dariusz Peric, David Bornand, Sonia Ouadi, Nicolas Sierro, Ansgar Büttner, Nikolai V Ivanov, Patrick Vanscheeuwijck, Julia Hoeng, Manuel C Peitsch

Macroscopic information-based taste representations in insular cortex are shaped by stimulus concentration

岛叶皮层中基于宏观信息的味觉表征受刺激浓度的影响。

Porcu, Emanuele; Benz, Karsta M; Ball, Felix; Tempelmann, Claus; Hanke, Michael; Noesselt, Toemme

Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice

在为期 18 个月的 A/J 小鼠系统毒理学研究中,暴露于候选改良风险烟草产品 THS 2.2 的气溶胶对呼吸系统的影响

Bjoern Titz, Alain Sewer, Karsta Luettich, Ee Tsin Wong, Emmanuel Guedj, Catherine Nury, Thomas Schneider, Yang Xiang, Keyur Trivedi, Grégory Vuillaume, Patrice Leroy, Ansgar Büttner, Florian Martin, Nikolai V Ivanov, Patrick Vanscheeuwijck, Julia Hoeng, Manuel C Peitsch

Reduced Chronic Toxicity and Carcinogenicity in A/J Mice in Response to Life-Time Exposure to Aerosol From a Heated Tobacco Product Compared With Cigarette Smoke

与香烟烟雾相比,A/J 小鼠终生接触加热烟草制品气溶胶可降低其慢性毒性和致癌性

Ee Tsin Wong, Karsta Luettich, Subash Krishnan, Sin Kei Wong, Wei Ting Lim, Demetrius Yeo, Ansgar Büttner, Patrice Leroy, Grégory Vuillaume, Stéphanie Boué, Julia Hoeng, Patrick Vanscheeuwijck, Manuel C Peitsch

Comparison of the basic morphology and function of 3D lung epithelial cultures derived from several donors

不同供体来源的 3D 肺上皮培养物的基本形态和功能比较

David Bovard, Albert Giralt, Keyur Trivedi, Laurent Neau, Petros Kanellos, Anita Iskandar, Athanasios Kondylis, Karsta Luettich, Stefan Frentzel, Julia Hoeng, Manuel C Peitsch