Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
阳性选择 CRISPR 筛选揭示了一种寡糖基转移酶中存在可药物靶向的口袋，该酶是炎症信号传导至 NF-κB 所必需的。
期刊:Cell
影响因子:45.5
doi:10.1016/j.cell.2024.03.022
Benjamin L Lampson ,Ana S Ramίrez ,Marta Baro ,Lixia He ,Mudra Hegde ,Vidyasagar Koduri ,Jamie L Pfaff ,Ruth E Hanna ,Julia Kowal ,Nitin H Shirole ,Yanfeng He ,John G Doench ,Joseph N Contessa ,Kaspar P Locher ,William G Kaelin Jr
