Exploring Alternative Zinc-Binding Groups in Histone Deacetylase (HDAC) Inhibitors Uncovers DS-103 as a Potent Ethylhydrazide-Based HDAC Inhibitor with Chemosensitizing Properties.
探索组蛋白去乙酰化酶 (HDAC) 抑制剂中的替代锌结合基团，发现 DS-103 是一种具有化学增敏特性的强效乙基肼基 HDAC 抑制剂
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.4c02373
Stopper Daniel, Biermann Lukas, Watson Paris R, Li Jingyu, König Beate, Gaynes Matthew N, Pessanha de Carvalho Lais, Klose Jana, Hanl Maria, Hamacher Alexandra, Schäker-Hübner Linda, Ramsbeck Daniel, Held Jana, Christianson David W, Kassack Matthias U, Hansen Finn K
